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      Diabetes and Hypertension in India : A Nationally Representative Study of 1.3 Million Adults

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          Key Points

          Question

          How does the prevalence of diabetes and hypertension in India vary by geographical area and sociodemographic characteristics?

          Findings

          Diabetes and hypertension prevalence varied widely among states (by more than a factor of 6 for diabetes and more than a factor of 2 for hypertension); while household wealth and urban location were positively associated with both conditions, the prevalence of diabetes and hypertension among those older than 40 years in the poorest household wealth quintile in rural areas was nonetheless high (5.9% and 30.0%, respectively).

          Meaning

          The prevalence of diabetes and hypertension in India varies substantially by age, rural vs urban location, and state—knowledge that could be used to target relevant programs to those most in need.

          Abstract

          Importance

          Understanding how diabetes and hypertension prevalence varies within a country as large as India is essential for targeting of prevention, screening, and treatment services. However, to our knowledge there has been no prior nationally representative study of these conditions to guide the design of effective policies.

          Objective

          To determine the prevalence of diabetes and hypertension in India, and its variation by state, rural vs urban location, and individual-level sociodemographic characteristics.

          Design, Setting, and Participants

          This was a cross-sectional, nationally representative, population-based study carried out between 2012 and 2014. A total of 1 320 555 adults 18 years or older with plasma glucose (PG) and blood pressure (BP) measurements were included in the analysis.

          Exposures

          State, rural vs urban location, age, sex, household wealth quintile, education, and marital status.

          Main Outcomes and Measures

          Diabetes (PG level ≥126 mg/dL if the participant had fasted or ≥200 mg/dL if the participant had not fasted) and hypertension (systolic BP≥140 mm Hg or diastolic BP≥90 mm Hg).

          Results

          Of the 1 320 555 adults, 701 408 (53.1%) were women. The crude prevalence of diabetes and hypertension was 7.5% (95% CI, 7.3%-7.7%) and 25.3% (95% CI, 25.0%-25.6%), respectively. Notably, hypertension was common even among younger age groups (eg, 18-25 years: 12.1%; 95% CI, 11.8%-12.5%). Being in the richest household wealth quintile compared with being in the poorest quintile was associated with only a modestly higher probability of diabetes (rural: 2.81 percentage points; 95% CI, 2.53-3.08 and urban: 3.47 percentage points; 95% CI, 3.03-3.91) and hypertension (rural: 4.15 percentage points; 95% CI, 3.68-4.61 and urban: 3.01 percentage points; 95% CI, 2.38-3.65). The differences in the probability of both conditions by educational category were generally small (≤2 percentage points). Among states, the crude prevalence of diabetes and hypertension varied from 3.2% (95% CI, 2.7%-3.7%) to 19.9% (95% CI, 17.6%-22.3%), and 18.0% (95% CI, 16.6%-19.5%) to 41.6% (95% CI, 37.8%-45.5%), respectively.

          Conclusions and Relevance

          Diabetes and hypertension prevalence is high in middle and old age across all geographical areas and sociodemographic groups in India, and hypertension prevalence among young adults is higher than previously thought. Evidence on the variations in prevalence by state, age group, and rural vs urban location is critical to effectively target diabetes and hypertension prevention, screening, and treatment programs to those most in need.

          Abstract

          This cross-sectional, nationally representative, population-based study determines the prevalence of diabetes and hypertension in India, and its variation by state, rural vs urban location, and individual-level sociodemographic characteristics.

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          Author and article information

          Journal
          JAMA Intern Med
          JAMA Intern Med
          JAMA Intern Med
          JAMA Internal Medicine
          American Medical Association
          2168-6106
          2168-6114
          29 January 2018
          March 2018
          29 January 2019
          : 178
          : 3
          : 363-372
          Affiliations
          [1 ]Department of Global Health and Population, Harvard T. H. Chan School of Public Health, Boston, Massachusetts
          [2 ]Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts
          [3 ]Department of Economics & Centre for Modern Indian Studies, University of Goettingen, Göttingen, Germany
          [4 ]MRC/Wits Rural Public Health and Health Transitions Research Unit, School of Public Health, Education Campus, University of Witwatersrand, Johannesburg, South Africa
          [5 ]Centre for Global Health, King's College London, London, England
          [6 ]Indian Institute of Public Health, Gandhinagar, India
          [7 ]Public Health Foundation of India, Delhi NCR, India
          [8 ]Institute of Public Health, Heidelberg University, Heidelberg, Germany
          [9 ]Africa Health Research Institute, Mtubatuba, South Africa
          Author notes
          Article Information
          Corresponding Author: Lindsay M. Jaacks, PhD, Department of Global Health and Population, Harvard T. H. Chan School of Public Health, 655 Huntington Ave, Boston, MA 02115 ( jaacks@ 123456hsph.harvard.edu ).
          Accepted for Publication: November 24, 2017.
          Published Online: January 29, 2018. doi:10.1001/jamainternmed.2017.8094
          Author Contributions: Dr Jaacks had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
          Study concept and design: Geldsetzer, Manne-Goehler, Davies, Awasthi, Vollmer, Jaacks, Bärnighausen, Atun.
          Acquisition, analysis, or interpretation of data: Geldsetzer, Manne-Goehler, Theilmann, Davies, Awasthi, Jaacks, Bärnighausen, Atun.
          Drafting of the manuscript: Geldsetzer.
          Critical revision of the manuscript for important intellectual content: Geldsetzer, Manne-Goehler, Theilmann, Davies, Awasthi, Vollmer, Jaacks, Bärnighausen, Atun.
          Statistical analysis: Geldsetzer, Theilmann, Vollmer.
          Obtained funding: Geldsetzer, Jaacks.
          Study supervision: Davies, Jaacks, Bärnighausen, Vollmer, Atun.
          Conflict of Interest Disclosures: None reported.
          Additional Information: Drs Vollmer, Jaacks, Bärnighausen, and Atun are co–senior authors.
          Article
          PMC5885928 PMC5885928 5885928 ioi170126
          10.1001/jamainternmed.2017.8094
          5885928
          29379964
          984f9050-4b8b-4ba3-a1c8-d40386bf0cda
          Copyright 2018 American Medical Association. All Rights Reserved.
          History
          : 2 October 2017
          : 7 November 2017
          : 24 November 2017
          Categories
          Research
          Research
          Original Investigation
          Online First

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