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      Difficulties in research of Chinese medicine polysaccharides

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          Abstract

          Polysaccharides from Chinese medicines are attracting increasing attention to their wide range of valuable biological activities. As these polysaccharides are mostly from edible materials, their safety can be greatly ensured. Therefore, the Chinese medicine polysaccharides have been the focus of research and development of new drugs and health products. However, there are rarely successful cases. Here, based on the authors’ own research experience, the difficulties and challenges in chemical analysis and mechanism study of Chinese medicine polysaccharides are discussed, in the hope of eliciting more innovative ideas and solutions.

          Author and article information

          Journal
          CJNM
          Chinese Journal of Natural Medicines
          Elsevier BV
          1875-5364
          20 December 2019
          : 17
          : 12
          : 883-886
          Affiliations
          [1] 1 School of Chinese Medicine, Hong Kong Baptist University, Hong Kong 999077, China
          Author notes
          *Corresponding author: HAN Quan-Bin, E-mail: simonhan@ 123456hkbu.edu.hk

          Δ These authors contributed equally to this work.

          These authors have no conflict of interest to declare.

          Dedicated to Professor SUN Han-Dong on the Occasion of His 80th Birthday

          Article
          S1875-5364(19)30107-4
          10.1016/S1875-5364(19)30107-4
          c9d0544c-71c3-4c40-a260-f74ea8f95018
          Copyright © 2019 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.
          History
          : 09 November 2019
          Funding
          Funded by: HKSAR Innovation and Technology Fund
          Award ID: ITS/311/09
          Funded by: General Research Fund
          Award ID: 12100615
          Funded by: General Research Fund
          Award ID: 22100014
          Funded by: General Research Fund
          Award ID: 12100818
          Funded by: Health Medical Research Fund
          Award ID: 11122531
          Funded by: Health Medical Research Fund
          Award ID: 14150521
          Funded by: National Natural Sciences Foundation in China
          Award ID: 81473341
          Funded by: Hong Kong Baptist University
          Award ID: MPCF-001-2014/2015
          Funded by: Hong Kong Baptist University
          Award ID: RC-IRMS/14-15/06
          Funded by: Hong Kong Baptist University
          Award ID: FRG2/17-18/060
          Funded by: Hong Kong Baptist University
          Award ID: FRG2/16-17/002
          This research was supported by the HKSAR Innovation and Technology Fund (ITF, Tier 3, No. ITS/311/09), General Research Fund (Nos. 12100615, 22100014, and 12100818), Health Medical Research Fund (Nos. 11122531 and 14150521), National Natural Sciences Foundation in China (No. 81473341), and Hong Kong Baptist University (RC-start up grant, Nos. MPCF-001-2014/2015, RC-IRMS/14-15/06, FRG2/17-18/060, and FRG2/16-17/002).
          Categories
          Editorial

          Medicine,Pharmaceutical chemistry,Pharmacology & Pharmaceutical medicine,Complementary & Alternative medicine
          Polysaccharides,Chemical analysis,Mechanism study

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