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      Acute stress symptoms in general population during the first wave of COVID lockdown in Italy: Results from the COMET trial

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          Abstract

          Background

          The coronavirus disease of 2019 (COVID‐19) pandemic is an unprecedented traumatic event that has severely impacted social, economic, and health well‐being worldwide. The COvid Mental hEalth Trial was specifically designed to evaluate the impact of the COVID‐19 pandemic and its containment measures on the mental health of the Italian general population in terms of COVID‐19‐related acute stress disorder (ASD) symptoms.

          Methods

          The present cross‐sectional study is based on an online survey carried out in the period March–May 2020. Italian general adult population was invited to compile an anonymous survey, which included the severity of acute stress symptoms scale/National Stressful Events Survey Short Scale to investigate the occurrence and severity of ASD symptoms.

          Results

          The final sample consisted of 20,720 participants. During the lockdown, subjects with pre‐existing mental health problems reported a statistically significant higher risk of acute post‐traumatic symptoms compared to the general population ( B: 2.57; 95% CI:2.04–3.09; p < .0001) and health care professionals ( B: .37; 95% CI: .02–0.72; p < .05). According to multivariate regression models, the levels of acute post‐traumatic symptoms ( p < .0001) were higher in younger and female respondents. Social isolation and sleep disorder/insomnia represented positive predictors of acute stress ( B = 3.32, 95% CI = 3.08–3.57).

          Conclusions

          Concerns about the risk of infection as well as social isolation caused a higher incidence of acute post‐traumatic stress symptoms that may predict the subsequent development of post‐traumatic stress disorder symptoms in the long term.

          Abstract

          In our paper, we analyzed the impact of COVID‐19 pandemic on the general population in Italy, during the first phase of the lockdown. In particular, data were collected from more than 20,000 persons from the general population using the severity of acute stress symptoms scale, together with several other validated assessment tools.

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          Most cited references92

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          Diagnostic and Statistical Manual of Mental Disorders

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            Development of a new resilience scale: the Connor-Davidson Resilience Scale (CD-RISC).

            Resilience may be viewed as a measure of stress coping ability and, as such, could be an important target of treatment in anxiety, depression, and stress reactions. We describe a new rating scale to assess resilience. The Connor-Davidson Resilience scale (CD-RISC) comprises of 25 items, each rated on a 5-point scale (0-4), with higher scores reflecting greater resilience. The scale was administered to subjects in the following groups: community sample, primary care outpatients, general psychiatric outpatients, clinical trial of generalized anxiety disorder, and two clinical trials of PTSD. The reliability, validity, and factor analytic structure of the scale were evaluated, and reference scores for study samples were calculated. Sensitivity to treatment effects was examined in subjects from the PTSD clinical trials. The scale demonstrated good psychometric properties and factor analysis yielded five factors. A repeated measures ANOVA showed that an increase in CD-RISC score was associated with greater improvement during treatment. Improvement in CD-RISC score was noted in proportion to overall clinical global improvement, with greatest increase noted in subjects with the highest global improvement and deterioration in CD-RISC score in those with minimal or no global improvement. The CD-RISC has sound psychometric properties and distinguishes between those with greater and lesser resilience. The scale demonstrates that resilience is modifiable and can improve with treatment, with greater improvement corresponding to higher levels of global improvement. Copyright 2003 Wiley-Liss, Inc.
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              Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: A systematic review and meta-analysis

              Highlights • At least one in five healthcare professionals report symptoms of depression and anxiety. • Almost four in 10 healthcare workers experience sleeping difficulties and/or insomnia. • Rates of anxiety and depression were higher for female healthcare workers and nursing staff. • Milder mood symptoms are common and screening should aim to identify mild and sub-threshold syndromes.
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                Author and article information

                Contributors
                gaia.sampogna@gmail.com
                Journal
                Brain Behav
                Brain Behav
                10.1002/(ISSN)2157-9032
                BRB3
                Brain and Behavior
                John Wiley and Sons Inc. (Hoboken )
                2162-3279
                21 November 2023
                December 2023
                : 13
                : 12 ( doiID: 10.1002/brb3.v13.12 )
                : e3314
                Affiliations
                [ 1 ] Department of Clinical and Experimental Medicine University of Pisa Pisa Italy
                [ 2 ] Department of Psychiatry University of Campania “L. Vanvitelli” Naples Italy
                [ 3 ] Department of Medicine, Surgery and Health Sciences University of Trieste and Department of Mental Health, Azienda Sanitaria Universitaria Giuliano Isontina–ASUGI Trieste Italy
                [ 4 ] Department of Medicine and Surgery University of Milan Bicocca Milano Italy
                [ 5 ] Center for Behavioral Sciences and Mental Health National Institute of Health Rome Italy
                [ 6 ] Neuroscience Research Center, Department of Biomedical and Clinical Sciences and Aldo Ravelli Center for Neurotechnology and Brain Therapeutic University of Milan Milano Italy
                [ 7 ] Department of Psychiatry and Behavioral Sciences Stanford University Stanford California USA
                [ 8 ] Institute of Psychiatry, Department of Neurosciences and Rehabilitation University of Ferrara Ferrara Italy
                [ 9 ] Department of Neurosciences, Mental Health and Sensory Organs, Faculty of Medicine and Psychology Sapienza University of Rome Rome Italy
                [ 10 ] Department of Neuroscience, Section of Psychiatry University Cattolica del Sacro Cuore Rome Italy
                [ 11 ] Department of Neuroscience, Sensory organs and Thorax, Department of Psychiatry Fondazione Policlinico A. Gemelli IRCCS Rome Italy
                [ 12 ] Department of Psychiatry University of Perugia Perugia Italy
                [ 13 ] Clinical Psychiatry Unit Department of Clinical Neurosciences Università Politecnica delle Marche Ancona Italy
                Author notes
                [*] [* ] Correspondence

                Gaia Sampogna, Department of Psychiatry, University of Campania “L. Vanvitelli”, Naples, Italy. Email: gaia.sampogna@ 123456gmail.com

                [*]

                C. Carmassi and G. Sampogna share first authorship.

                Author information
                https://orcid.org/0000-0002-9547-2793
                https://orcid.org/0000-0001-8995-9020
                https://orcid.org/0000-0002-6926-0762
                Article
                BRB33314
                10.1002/brb3.3314
                10726770
                37990771
                c1fd240e-23e1-463b-a613-80c64a091afe
                © 2023 The Authors. Brain and Behavior published by Wiley Periodicals LLC.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 27 September 2023
                : 28 July 2023
                : 25 October 2023
                Page count
                Figures: 1, Tables: 3, Pages: 12, Words: 8908
                Categories
                Original Article
                Original Articles
                Custom metadata
                2.0
                December 2023
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.3.6 mode:remove_FC converted:18.12.2023

                Neurosciences
                acute stress,acute stress symptoms,asd,covid‐19,lockdown,post‐traumatic stress symptoms,ptsd

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