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      Mini-thoracotomy in redo mitral valve surgery: safety and efficacy of a standardized procedure

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          Abstract

          Background

          Re-operative mitral valve surgery is sometimes burdened by a greater technical difficulty and a higher complications rate than the first operation. Minimally invasive cardiac surgery has become routine, and it could significantly reduce the surgical risk in redo surgery. The objective of our retrospective observational study is to assess the results of cardiac reoperations in patients with mitral valve disease approached trough a 5–7 cm right mini-thoracotomy.

          Methods

          From February 2017 to December 2019, 65 patients underwent re-operative mitral valve surgery in our institution. Cardiopulmonary bypass (CPB) was started by cannulation of the femoral and jugular vein and femoral artery or alternatively right axillary artery. Patients enrolled had a mean age of 66.6±11.5 years. Patients were divided into three groups based on the procedure adopted: external aortic cross-clamp (EAC), EndoAortic balloon occlusion (EABO) and ventricular fibrillation (VF). Major complications were evaluated and compared with a propensity matched population of patients undergoing elective isolated mitral valve surgery via right minithoracotomy (MVS).

          Results

          The average time between last operation and reoperation was 7.1±3.4 years. Fourteen patients (21%) underwent mitral valve repair and 51 patients (78%) underwent mitral valve replacement; 9 patients (14%) received tricuspid valve surgery. There was no statistically significant difference in CPB time between the groups. Seven patients (11%) had a postoperative renal failure, 5 patients (8%) underwent surgical reopening for bleeding; incidence of post-operative stroke and pace-maker implantation was 3% for both. No deaths were registered during in-hospital stay and at 30-days echocardiographic control all patients respect the criterions of device success according with MVARC. Propensity matched patients of group redo had a longer CPB time (100.8±42.7 versus 72.8±16.7 min, P<0.001) and cross-clamp time (71.9±30.7 versus 59±10.7 min, P<0.001) respect to first operation mitral valve surgery patients.

          Conclusions

          Minimally invasive mitral valve redo surgery is a safe procedure. Less invasive techniques in redo surgery could minimize morbidity and mortality without prolonging the duration of CPB.

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          Most cited references29

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          2017 ESC/EACTS Guidelines for the management of valvular heart disease.

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            2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.

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              Pathogenesis of myocardial ischemia-reperfusion injury and rationale for therapy.

              Since the initial description of the phenomenon by Jennings et al 50 years ago, our understanding of the underlying mechanisms of reperfusion injury has grown significantly. Its pathogenesis reflects the confluence of multiple pathways, including ion channels, reactive oxygen species, inflammation, and endothelial dysfunction. The purposes of this review are to examine the current state of understanding of ischemia-reperfusion injury, as well as to highlight recent interventions aimed at this heretofore elusive target. In conclusion, despite its complexity our ongoing efforts to mitigate this form of injury should not be deterred, because nearly 2 million patients annually undergo either spontaneous (in the form of acute myocardial infarction) or iatrogenic (in the context of cardioplegic arrest) ischemia-reperfusion. Copyright (c) 2010 Elsevier Inc. All rights reserved.
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                Author and article information

                Journal
                J Thorac Dis
                J Thorac Dis
                JTD
                Journal of Thoracic Disease
                AME Publishing Company
                2072-1439
                2077-6624
                September 2021
                September 2021
                : 13
                : 9
                : 5363-5372
                Affiliations
                [1 ]Cardiac Surgery Unit, AOR San Carlo Hospital, Basilicata , Italy;
                [2 ]deptKároly Rácz School of PhD Studies , Semmelweis University , Budapest, Hungary;
                [3 ]Cardiac Anaesthesia and Cardiac-Intesive Care, AOR San Carlo Hospital, Basilicata , Italy
                Author notes

                Contributions: (I) Conception and design: F Prestipino, Á Nagy; (II) Administrative support: None; (III) Provision of study materials or patients: None; (IV) Collection and assembly of data: F Prestipino, R D’Ascoli, G Paternoster, E Manzan; (V) Data analysis and interpretation: F Prestipino, G Luzi; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors.

                Correspondence to: Filippo Prestipino, MD. Cardiac Surgery Unit, AOR San Carlo Hospital, Basilicata, Italy. Email: filippo.prestipino@ 123456libero.it .
                [^]

                ORCID: 0000-0002-4668-0633.

                Article
                jtd-13-09-5363
                10.21037/jtd-21-667
                8482333
                34659803
                b2998879-a20e-483e-b676-289ff7fa284a
                2021 Journal of Thoracic Disease. All rights reserved.

                Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

                History
                : 15 April 2021
                : 06 August 2021
                Categories
                Original Article

                mitral valve repair,mitral valve replacement,mini-thoracotomy,redo surgery

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