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      Investigation of EBT3 radiochromic film's response to humidity

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          Abstract

          Purpose

          The aim of this work is to investigate the effects of immersing EBT3 radiochromic film in water and to evaluate its contribution to the total uncertainty in dose determination.

          Materials and methods

          We used 3 cm × 3 cm EBT3 radiochromic films irradiated in the range of 0–70 Gy to study the impact of water immersion on the change in net optical density. These films were placed in a water container for a period of 24 h. The net optical density was measured before (0 h) and after of the immersion in water (1, 3, 6, 12, 18, and 24 h). The absorbance spectrum of the EBT3 radiochromic film was measured at 0 h and 24 h after immersion in water. The uncertainty in dose determination due to the effects of keeping the EBT3 radiochromic film submerged in water at 0, 1, and 24 h were recorded in the red, green, and blue channels.

          Results

          We observed an increase in the net optical density as an effect on the film due to its immersion in water. The penetration of the water at the edges of the radiochromic film was observed to be a function of time during which the film remained in the water. On the other hand, the penetration of water at the edges of the film was found to be independent of irradiation dose.

          Conclusions

          EBT3 radiochromic film is found more resistant to water penetration through the edges than its predecessors. However, there is evidence that suggest that liquid water damage the Nylon cover layer of the film by changing its optical properties. Therefore, it is recommended to build a new calibration curve for radiochromic films for a specific situation involving dose measurements in liquid water.

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          Most cited references17

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          Radiochromic film dosimetry: recommendations of AAPM Radiation Therapy Committee Task Group 55. American Association of Physicists in Medicine.

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            Dosimetric characterization and use of GAFCHROMIC EBT3 film for IMRT dose verification

            Radiochromic film has become an important tool to verify dose distributions in highly conformal radiation therapy such as IMRT. Recently, a new generation of these films, EBT3, has become available. EBT3 has the same composition and thickness of the sensitive layer of the previous EBT2 films, but its symmetric layer configuration allows the user to eliminate side orientation dependence, which is reported for EBT2 films. The most important EBT3 characteristics have been investigated, such as response at high‐dose levels, sensitivity to scanner orientation and postirradiation coloration, energy and dose rate dependence, and orientation dependence with respect to film side. Additionally, different IMRT fields were measured with both EBT3 and EBT2 films and evaluated using gamma index analysis. The results obtained show that most of the characteristics of EBT3 film are similar to the EBT2 film, but the orientation dependence with respect to film side is completely eliminated in EBT3 films. The study confirms that EBT3 film can be used for clinical practice in the same way as the previous EBT2 film. PACS number: 87.56.Fc
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              Comparison of Gafchromic EBT2 and EBT3 films for clinical photon and proton beams.

              Dose verification in highly conformal radiation therapy such as IMRT or proton therapy can benefit from the high spatial resolution offered by radio-chromic films such as Gafchromic EBT or EBT2. Recently, a new generation of these films, EBT3, has become available. The composition and thickness of the sensitive layer are the same as for the previous EBT2 films. The most important change is the symmetric layer configuration to eliminate side orientation dependence, which is reported for EBT2 films. The general film characteristics such as sensitivity to read-out orientation and postexposure darkening evolution of the new EBT3 film are evaluated. Film response has been investigated in clinical photon and proton beams and compared to former EBT2 films. Quenching effects in the proton Bragg peak region have been studied for both, EBT2 and EBT3 films. The general performance of EBT3 is comparable to EBT2, and the orientation dependence with respect to film side is completely eliminated in EBT3 films. Response differences of EBT2 and EBT3 films are of the same order of magnitude as batch-to-batch variations observed for EBT2 films. No significant difference has been found for both generations of EBT films between photon and proton exposure. Depth dose measurements of EBT2 and EBT3 show an excellent agreement, though underestimating dose by up to 20% in the Bragg peak region. The symmetric configuration of EBT3 presents a major improvement for film handling. EBT3 has similar dosimetric performance as its precursor EBT2 and can, thus, be applied to dose verification in IMRT in the same way. For dose verification in proton therapy the underresponse in the Bragg peak region has to be taken into account.
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                Author and article information

                Contributors
                oagarciag@innn.edu.mx , amanda.garcia.g@gmail.com
                Journal
                J Appl Clin Med Phys
                J Appl Clin Med Phys
                10.1002/(ISSN)1526-9914
                ACM2
                Journal of Applied Clinical Medical Physics
                John Wiley and Sons Inc. (Hoboken )
                1526-9914
                29 April 2018
                May 2018
                : 19
                : 3 ( doiID: 10.1002/acm2.2018.19.issue-3 )
                : 283-290
                Affiliations
                [ 1 ] Laboratorio de Fotomedicina, Biofotónica y Espectroscopia Láser de Pulsos Ultracortos, Facultad de Medicina Universidad Autónoma del Estado de México Toluca México
                [ 2 ] Laboratorio de Física Médica & Unidad de Radiocirugía Instituto Nacional de Neurología y Neurocirugía Mexico City México
                [ 3 ] Departamento de Oncología & Departamento de Física y Astronomía Universidad de Calgary Calgary AB Canada
                Author notes
                [*] [* ] Author to whom correspondence should be addressed. Olivia Amanda García‐Garduño

                E‐mails: oagarciag@ 123456innn.edu.mx ; amanda.garcia.g@ 123456gmail.com

                Telephone: +52 5556063822 × 4471, 5021; Fax: +52 555606 2907

                Article
                ACM212337
                10.1002/acm2.12337
                5978557
                29707904
                91b27ee2-4292-40a7-9616-45520c2e07fa
                © 2018 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 19 October 2017
                : 10 January 2018
                : 20 March 2018
                Page count
                Figures: 7, Tables: 3, Pages: 8, Words: 5406
                Funding
                Funded by: National Council of Science and Technology (CONACYT)
                Award ID: SALUD‐1‐2015‐261405
                Categories
                87.55.km
                Radiation Oncology Physics
                Radiation Oncology Physics
                Custom metadata
                2.0
                acm212337
                May 2018
                Converter:WILEY_ML3GV2_TO_NLMPMC version:version=5.4.0 mode:remove_FC converted:31.05.2018

                ebt3 radiochromic film,humidity,net optical density
                ebt3 radiochromic film, humidity, net optical density

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