Cerebral hemodynamic impairment: assessment with resting-state functional MR imaging.

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Abstract

To test the feasibility of noninvasive global assessment of cerebral hemodynamic impairment with use of resting-state blood oxygenation level-dependent functional magnetic resonance (MR) imaging.

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Author and article information

Journal

Journal ID (iso-abbrev): Radiology

Title: Radiology

Publisher: Radiological Society of North America (RSNA)

ISSN (Electronic): 1527-1315

ISSN (Print): 0033-8419

Publication date (Electronic): Feb 2014

Volume: 270

Issue: 2

Affiliations

[1 ] From the Departments of Radiology (S.A., A.K., K.O.) and Neurosurgery (N.S.), Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Article

Publisher Item ID: radiol.13130982

DOI: 10.1148/radiol.13130982

PubMed ID: 24072777

SO-VID: 8bab02bf-5c86-41de-8aad-32c58806f747

History

Data availability:

Comments

Ahmed Khalil wrote:

This study closely followed the original time shift analysis (TSA) paper (Lv et al., Annals of Neurology 2013).

Study sample consisted of six acute stroke patients and five patients with chronic hypoperfusion and no neurologic impairment.

Compared perfusion lesions derived from TSA of rsfMRI data with perfusion lesions derived from dynamic susceptibility contrast MRI (DSC-MRI; specifically, time-to-peak aka TTP maps).

Analysis based on spatial overlap and a comparison of lesion volumes.

This study was the first to show that hypoperfusion can be seen on TSA maps even in the absence of overt neurological impairment.

2020-03-31 08:32 UTC

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