When poorly conducted systematic reviews and meta-analyses can mislead: a critical appraisal and update of systematic reviews and meta-analyses examining the effects of probiotics in the treatment of functional constipation in children.

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Abstract

Recent systematic reviews and meta-analyses on the efficacy of probiotics in the treatment of functional constipation in children have yielded conflicting results.

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Journal ID (iso-abbrev): Am J Clin Nutr

Title: The American journal of clinical nutrition

Publisher: Oxford University Press (OUP)

ISSN (Electronic): 1938-3207

ISSN (Print): 0002-9165

Publication date (Electronic): July 01 2019

Volume: 110

Issue: 1

Affiliations

[1 ] Illawarra Health and Medical Research Institute & School of Medicine, Faculty of Science, Medicine, and Health, University of Wollongong, Wollongong, New South Wales, Australia.

Article

Publisher Item ID: 5498646

DOI: 10.1093/ajcn/nqz071

PubMed ID: 31127810

SO-VID: 52125655-d0ef-4489-b9fa-347c62c991a1

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Keywords: children,critical appraisal,functional constipation,meta-analysis,probiotics,randomized controlled trials,risk of bias,systematic review

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Keywords: children, critical appraisal, functional constipation, meta-analysis, probiotics, randomized controlled trials, risk of bias, systematic review

When poorly conducted systematic reviews and meta-analyses can mislead: a critical appraisal and update of systematic reviews and meta-analyses examining the effects of probiotics in the treatment of functional constipation in children.

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