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      Posterior arthrodesis of C1-C3 for the stabilization of multiple unstable upper cervical fractures with spinal cord compromise : A case report and literature review

      case-report

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          Abstract

          Background:

          Multiple fractures of the atlas and axis are rare. The management of multiple fragment axis fractures and unstable atlas fractures is still challenging for the spinal surgeon. There are no published reports of similar fractures with 3-part fracture of axis associated with an unstable atlas fracture.

          Case summary:

          We present a patient with concurrent axis and atlas fractures, which have not been reported. The patient suffered hyperextension injury with neck pain and numbness of the bilateral upper extremity associated with weakness after a 2-m fall. The axis fractures included an odontoid type IIA fracture and traumatic spondylolisthesis of C2-C3. The atlas fracture was unstable. The neurological examination manifested as central canal syndrome, which was due to the hyperextension injury of cervical spine and spondylolisthesis of C2-C3. The patient was diagnosed as multiple unstable upper cervical fractures with spinal cord compromise. We performed posterior arthrodesis of C1-C3. Postoperatively, the patient showed neurological improvement, and C1-C3 had fused at the 3-month follow-up.

          Conclusion:

          Posterior arthrodesis of C1-C3 could provide a stable fixation for the 3 parts of axis (an odontoid type IIA fracture and traumatic spondylolisthesis of C2-C3) combined an unstable atlas fracture. Both the patient and the doctor were satisfied with the results of the treatment. So posterior arthrodesis of C1-C3 is a suitable treatment option for the treatment of a concurrent unstable atlas fracture and multiple fractures of the axis.

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          Most cited references16

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          Morphometric evaluation of screw fixation in atlas via posterior arch and lateral mass.

          This study is a result of manual and radiologic measurements of 50 isolated anatomic specimens of C1 and five patients of atlantoaxial instability treated by screw fixation via posterior arch and lateral mass. To investigate the feasibility of screw placement via posterior arch and lateral mass in atlas. Several types of posterior approaches have been adopted for stabilization and fusion of atlantoaxial complex. Before this study, Gallie in 1939 gave a report on a posterior wiring technique that depended on a structural bone graft. Since then, double-looped wiring with two bone grafts and Halifax clamp technique had been introduced. A transarticular screw fixation technique was introduced by Magerl and Seeman in 1987, and a C1 lateral mass screw fixation technique was described by Harms in 2001. However, the feasibility of screw fixation in atlas via posterior arch and lateral mass has not been addressed until now. Fifty dry samples of atlas were measured manually and radiologically with vernier calipers, protractors, and CT. The parameters of posterior arch, lateral mass, vertebral artery groove, axis length of screw path via posterior arch and lateral mass, the entry point, and screw direction were measured. Five patients of atlantoaxial instability were treated with this technique and the radiographs and CT scans were evaluated after surgery. The longest trajectory distance of the screw path was about 30 mm. The outer thickness at the thinnest part of groove was 4.58 mm, and it was found to be <4 mm in four cases (8%). The entry point is 18-20 mm lateral to the midline and 2 mm superior to the inferior border of posterior arch. The direction of screw placement is perpendicular to the coronal plane and about 5 degrees cephalad to the transverse plane. Ten screws via posterior arch and lateral mass were placed properly, without incidence of nerve or blood vessel injury in clinical practice. Atlas is capable for screw fixation via its posterior arch and lateral mass.
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            Posterior stabilization of the cervical spine with hook plates.

            Hook-plate fixation is designed for posterior cervical stabilization from C2 to C7. Indications remain the same as for standard posterior fixations. The prime indications are discoligamentous injuries. The plates are hooked under the lower laminas and attached to the articular masses of the upper vertebra by oblique screws. An H-graft is placed between the spinous processes. The vertebrae are compressed together by the plates at three points, the facet joints, and graft. The resulting pre-stressed system is stable in all directions. A protocol for safe reduction of cervical dislocations is observed. Of 70 patients treated from 1979 to 1986, 51 were examined 12-54 months after surgery. All fusions consolidated. Two neurologic complications not attributable to the fixation occurred. Other major complications were not seen.
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              Anatomic suitability of the C1-C2 complex for pedicle screw fixation.

              A computed tomography (CT) study of 60 consecutive patients (120 sides) was performed to assess suitability for either transarticular or pedicle screw fixation. A C1 lateral mass and C2 pedicle screw fixation with a rigid cantilever beam system has been described. The anatomic constraints relevant for this technique have not. Fifty consecutive patients underwent standard CT of the cervical spine. Pedicle and transarticular screw trajectories were plotted, and the maximum safe diameter for screw placement was determined for each trajectory. Also, trajectories were plotted in 10 additional patients with known craniocervical junction abnormalities using three-dimensional (3-D) imaging and computer-aided navigation tools. Screw placement was considered feasible if a 4-mm diameter trajectory could be plotted without impingement on neural or vascular structures. Four-millimeter diameter pedicle screws could be placed in 91 of 100 C2 pedicles in the CT studies and in 20 of 20 pedicles in the 3-D studies. Four-millimeter diameter C1-C2 transarticular screws could be placed in 94 of 100 sides in the CT study and in 19 of 20 sides in the 3-D study. Four sides could tolerate a C2 pedicle screw and not a transarticular screw; the opposite situation existed in five sides. Placement of screws into C1 was not an issue in any patient. The mean maximum diameter of potential transarticular screws was 6.5 mm, and the mean maximum diameter of the pedicle screws was 5.3 mm (P < 0.01). C1-C2 pedicle screw fixation is a technique that appears to be widely applicable and may represent an alternative fixation technique in selected patients.
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                Author and article information

                Journal
                Medicine (Baltimore)
                Medicine (Baltimore)
                MEDI
                Medicine
                Wolters Kluwer Health
                0025-7974
                1536-5964
                January 2017
                10 January 2017
                : 96
                : 1
                : e5841
                Affiliations
                Department of Orthopaedics, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
                Author notes
                []Correspondence: Fangcai Li, Department of Orthopaedics, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, #88 Jiefang Road, Hangzhou 310009, Zhejiang, China (e-mail: lifangcai321@ 123456163.com)
                Article
                MD-D-16-05770 05841
                10.1097/MD.0000000000005841
                5228704
                28072744
                46d17e0a-d771-4c99-a727-a44e34519973
                Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc.

                This is an open access article distributed under the Creative Commons Attribution-NoDerivatives License 4.0, which allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author. http://creativecommons.org/licenses/by-nd/4.0

                History
                : 15 September 2016
                : 10 December 2016
                : 15 December 2016
                Categories
                7100
                Research Article
                Clinical Case Report
                Custom metadata
                TRUE

                multifragmentary axis fractures,posterior fusion,unstable atlas fractures

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