Factors associated with major bleeding events: insights from the ROCKET AF trial (rivaroxaban once-daily oral direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation).

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Abstract

This study sought to report additional safety results from the ROCKET AF (Rivaroxaban Once-daily oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation).

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Author and article information

Journal

Journal ID (iso-abbrev): J. Am. Coll. Cardiol.

Title: Journal of the American College of Cardiology

ISSN (Electronic): 1558-3597

ISSN (Print): 0735-1097

Publication date (Electronic): Mar 11 2014

Volume: 63

Issue: 9

Affiliations

[1 ] Canadian Heart Research Centre and Terrence Donnelly Heart Centre, Division of Cardiology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada. Electronic address: goodmans@chrc.net.

[2 ] Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina.

[3 ] Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand.

[4 ] Bayer HealthCare Pharmaceuticals, Montville, New Jersey.

[5 ] Janssen Research and Development, Raritan, New Jersey.

[6 ] Cardiovascular Institute, Mount Sinai Medical Center, New York, New York.

[7 ] Ruprecht-Karls-University, Heidelberg, Germany.

[8 ] Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

[9 ] Royal Perth Hospital, Perth, Australia.

[10 ] Hospital of the University of Münster, Münster, Germany.

[11 ] University of Edinburgh and Royal Infirmary of Edinburgh, Edinburgh, Scotland, United Kingdom.

[12 ] Duke Clinical Research Institute and Duke Translational Medicine Institute, Duke University Medical Center, Durham, North Carolina.

Article

Publisher Item ID: S0735-1097(13)06208-6 Mid ID: NIHMS622088

DOI: 10.1016/j.jacc.2013.11.013

PMC ID: 4206565

PubMed ID: 24315894

SO-VID: 44d7e34f-c77e-46a7-86f4-622bfe193ad4

History

Keywords: anticoagulants,atrial fibrillation,hemorrhage

Data availability:

Keywords: anticoagulants, atrial fibrillation, hemorrhage

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