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      Sequelae and Other Conditions in Ebola Virus Disease Survivors, Sierra Leone, 2015

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          Abstract

          We rapidly assessed the health of Ebola virus disease (EVD) survivors in Kenema, Sierra Leone, by reviewing medical charts of all patients attending the Survivor Clinic of Kenema Government Hospital. Data were abstracted on signs and symptoms at every attendance. As of November 2015, a total of 621 attendances by 115 survivors with laboratory-confirmed EVD were made to the Survivor Clinic. Most (60.9%) survivors were women. Survivors’ median age was 28 years (range 0.25–70 years). Survivors attended the clinic a median of 5 times (range 1–21 times) each, and the median time from EVD discharge to attendance was 261 days (range 4–504 days). The most commonly reported signs and symptoms among the 621 attendances were headache (63.1%), fever (61.7%), and myalgia (43.3%). Because health needs of EVD survivors are complex, rapid chart reviews at survivor clinics should be repeated regularly to assess the extent of illness and prioritize service delivery.

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          Sequelae of Ebola virus disease: the emergency within the emergency.

          As the massive outbreak of Ebola virus disease (EVD) in west Africa wanes, it has become increasingly clear that thousands of survivors have many sequelae, some of which might be very severe, such as arthritis and vision-threatening uveitis. The mental health effects of EVD on survivors and other family and community members is similarly profound. Furthermore, it is increasingly being recognised that Ebola virus might persist for weeks or months in selected body compartments of survivors, most notably in the semen of men, bringing risk of renewed transmission where it has previously been eliminated. These challenges to EVD survivors constitute a new emergency in terms of addressing individual patient need and to control the disease spread. In this Review, we assess what is known regarding the sequelae of EVD, including possible delayed virus clearance. We discuss some of the key challenges regarding the provision of care to survivors and implementation of necessary future research.
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            Early clinical sequelae of Ebola virus disease in Sierra Leone: a cross-sectional study.

            Limited data are available on the prevalence and predictors of clinical sequelae in survivors of Ebola virus disease (EVD). The EVD Survivor Clinic in Port Loko, Sierra Leone, has provided clinical care for 603 of 661 survivors living in the district. We did a cross-sectional study to describe the prevalence, nature, and predictors of three key EVD sequelae (ocular, auditory, and articular) in this cohort of EVD survivors.
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              Is Open Access

              Ebola Virus Disease Complications as Experienced by Survivors in Sierra Leone

              The main complications experienced by Ebola virus disease (EVD) survivors in our clinic were arthralgia and uveitis as described earlier. Treatment of EVD complications should be systematic and initiated as soon as possible to prevent severe disabilities such as blindness.
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                Author and article information

                Journal
                Emerg Infect Dis
                Emerging Infect. Dis
                EID
                Emerging Infectious Diseases
                Centers for Disease Control and Prevention
                1080-6040
                1080-6059
                January 2017
                : 23
                : 1
                : 66-73
                Affiliations
                [1]Public Health England, London, UK (H. Mohammed);
                [2]World Health Organization, Kenema, Sierra Leone (H. Mohammed, A.O. Vandy, R. Stretch, D. Otieno, M. Prajapati);
                [3]World Health Organization, Freetown, Sierra Leone (M. Calderon);
                [4]District Health Management Team, Kenema, Sierra Leone (M. Vandi)
                Author notes
                Address for correspondence: Hamish Mohammed, HIV & STI Department, National Infection Service, Public Health England, London NW9 5EQ, UK; email: hamish.mohammed@ 123456phe.gov.uk
                Article
                16-0631
                10.3201/eid2301.160631
                5176247
                27983503
                311aa1fb-a4ce-4aef-8c65-7735ad39bd5a
                History
                Categories
                Research
                Research
                Sequelae and Other Conditions in Ebola Virus Disease Survivors, Sierra Leone, 2015

                Infectious disease & Microbiology
                ebola virus disease,survivors,sequelae,sierra leone,viruses
                Infectious disease & Microbiology
                ebola virus disease, survivors, sequelae, sierra leone, viruses

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