GDF11 and the Mythical Fountain of Youth.

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Abstract

Identifying candidates that rejuvenate aged muscle stem cells is an important strategy toward developing therapies to treat age-related diseases. In this issue, Egerman et al. (2015) re-investigate the activity of GDF11 in myogenesis, recently suggested as an anti-aging agent, and instead find a potent inhibitory effect on skeletal muscle regeneration.

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Journal

Journal ID (iso-abbrev): Cell Metab.

Title: Cell metabolism

ISSN (Electronic): 1932-7420

ISSN (Print): 1550-4131

Publication date (Electronic): Jul 7 2015

Volume: 22

Issue: 1

Affiliations

[1 ] Sprott Center for Stem Cell Research, Ottawa Hospital Research Institute, Regenerative Medicine Program, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada; Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada.

[2 ] Sprott Center for Stem Cell Research, Ottawa Hospital Research Institute, Regenerative Medicine Program, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada; Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada. Electronic address: mrudnicki@ohri.ca.

Article

Publisher Item ID: S1550-4131(15)00221-1

DOI: 10.1016/j.cmet.2015.05.009

PubMed ID: 26003784

SO-VID: 30583cd5-6676-4cf2-ada7-edd66a31c048

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