12
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Multi-level experiences and determinants of alcohol misuse and illicit drug use among occupational groups at high-risk of HIV in sub-Saharan Africa: A thematic synthesis of qualitative findings

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          ABSTRACT

          Occupational groups at high-risk of HIV in sub-Saharan Africa (SSA) may be at increased risk of substance use because of occupation-related factors. We synthesised qualitative data on determinants and context of alcohol misuse and illicit drug use in these groups. We systematically searched five databases for qualitative studies reporting on alcohol misuse or illicit drug use in fisherfolk, uniformed personnel, miners, truckers, motorcycle taxi riders, and sex workers in SSA. Qualitative data and interpretations were extracted and synthesised using a systematic iterative process to capture themes and overarching concepts. We searched for papers published prior to January 2018. We identified 5692 papers, and included 21 papers in our review, published from 1993 to 2017. Most studies were conducted among fisherfolk ( n = 4) or sex workers ( n = 12). Ten papers reported on alcohol use alone, three on illicit drug use alone and eight on both. Substance use was commonly examined in the context of work and risky behaviour, key drivers identified included transactional sex, availability of disposable income, poverty, gender inequalities and work/living environments. Substance use was linked to risky behaviour and reduced perceived susceptibility to HIV. Our review underscores the importance of multilevel, integrated HIV prevention and harm reduction interventions in these settings.

          Related collections

          Most cited references54

          • Record: found
          • Abstract: found
          • Article: not found

          Appraising the quality of qualitative research.

          In the process of undertaking a meta-synthesis of qualitative studies of free-standing midwife-led units, the authors of this paper encountered a number of methodologically and epistemologically unresolved issues. One of these related to the assessment of the quality of qualitative research. In an iterative approach to scoping this issue, we identified eight existing checklists and summary frameworks. Some of these publications were opinion based, and some involved a synthesis of pre-existing frameworks. None of them provide a clear map of the criteria used in all their reviewed papers, and of the commonalities and differences between them. We critically review these frameworks and conclude that, although they are epistemologically and theoretically dense, they are excessively detailed for most uses. In order to reach a workable solution to the problem of the quality assessment of qualitative research, the findings from these frameworks and checklists were mapped together. Using a technique we have termed a 'redundancy approach' to eliminate non-essential criteria, we developed our own summary framework. The final synthesis was achieved through reflexive debate and discussion. Aspects of this discussion are detailed here. The synthesis is clearly rooted in a subjectivist epistemology, which views knowledge as constructed and hermeneutic in intent, encompassing individual, cultural and structural representations of reality.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Alcohol use and antiretroviral adherence: review and meta-analysis.

            Alcohol use is frequently implicated as a factor in nonadherence to highly active antiretroviral therapy (HAART). There have not been efforts to systematically evaluate findings across studies. This meta-analysis provides a quantitative evaluation of the alcohol-adherence association by aggregating findings across studies and examining potential moderators. Literature searches identified 40 qualifying studies totaling over 25,000 participants. Studies were coded on several methodological variables. In the combined analysis, alcohol drinkers were approximately 50%-60% as likely to be classified as adherent [odds ratio (OR) = 0.548, 95% confidence interval (CI): 0.490 to 0.612] compared with abstainers (or those who drank relatively less). Effect sizes for problem drinking, defined as meeting the National Institute on Alcohol Abuse and Alcoholism criteria for at-risk drinking or criteria for an alcohol use disorder, were greater (OR = 0.474, 95% CI = 0.408 to 0.550) than those reflecting any or global drinking (OR = 0.604, 95% CI = 0.531 to 0.687). Several variables moderated the alcohol-adherence association. Results support a significant and reliable association of alcohol use and medication nonadherence. Methodological variables seem to moderate this association and could contribute to inconsistent findings across studies. Future research would benefit from efforts to characterize theoretical mechanisms and mediators and moderators of the alcohol-adherence association.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              The association between HIV infection and alcohol use: a systematic review and meta-analysis of African studies.

              To summarize the association between alcohol use and human immunodeficiency virus (HIV) infection based on studies conducted in Africa, EMBASE and PubMed were searched for African studies that related alcohol use to HIV infection. Meta-analyses were conducted to obtain pooled univariate and multivariate relative risk estimates. Subgroup analyses were performed for studies having different sample types: males or females and population-based or high-risk, and ones that differentiated between problem and asymptomatic drinkers. Alcohol drinkers were more apt to be HIV+ than nondrinkers. The pooled unadjusted odds ratio (OR) from 20 studies was 1.70 (95% confidence interval, CI = 1.45-1.99). Results from 11 studies that adjusted for other risk factors produced a pooled risk estimate of 1.57 (95% CI = 1.42-1.72). Males and females had similar risk estimates, while studies involving high-risk samples tended to report larger pooled odds ratios than studies of the general population. When compared with nondrinkers, the pooled estimates of HIV risk were 1.57 (95% CI = 1.33-1.86) for non-problem drinkers versus 2.04 (95% CI = 1.61-2.58) for problem drinkers, a statistically significant difference (z = 2.08, P <0.04). Alcohol use was associated with HIV infection in Africa and alcohol-related interventions might help reduce further expansion of the epidemic.
                Bookmark

                Author and article information

                Journal
                Glob Public Health
                Glob Public Health
                RGPH
                rgph20
                Global Public Health
                Taylor & Francis
                1744-1692
                1744-1706
                2020
                23 October 2019
                : 15
                : 5
                : 715-733
                Affiliations
                [a ]Department of HIV interventions and Epidemiology, MRC/UVRI and LSHTM Uganda Research Unit , Entebbe, Uganda
                [b ]Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine , London, UK
                [c ]Department of Global Health and Development, London School of Hygiene and Tropical Medicine , London, UK
                [d ]Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine , London, UK
                [e ]MRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine , London, UK
                Author notes
                [CONTACT ] Monica O. Kuteesa monica.kuteesa@ 123456lshtm.ac.uk
                Author information
                http://orcid.org/0000-0003-4296-1398
                http://orcid.org/0000-0002-0583-5272
                http://orcid.org/0000-0003-1250-2967
                Article
                1679216
                10.1080/17441692.2019.1679216
                7175470
                31640453
                294cc494-99f4-4032-b3dc-ed017bd7f5e6
                © 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

                This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License ( http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

                History
                : 22 January 2019
                : 08 October 2019
                Page count
                Figures: 2, Tables: 2, Equations: 0, References: 78, Pages: 19
                Funding
                Funded by: UK Department for International Development 10.13039/501100000278
                Award ID: MR/K012126/1
                Funded by: EW 10.13039/100012036
                Award ID: MR/K012126/1
                Funded by: UK Medical Research Council 10.13039/501100000265
                This research was jointly funded by the UK Medical Research Council (MRC) and the UK Department for International Development (DFID) under the MRC/DFID Concordat agreement: [grant reference MR/K012126/1]; EW received salary funding from MRC: [grant reference MR/K012126/1]. The International AIDS Vaccine Initiative (made possible by the support of many donors, including: the Bill & Melinda Gates Foundation, the Ministry of Foreign Affairs of Denmark, Irish Aid, the Ministry of Finance of Japan in partnership with The World Bank, the Ministry of Foreign Affairs of the Netherlands, the Norwegian Agency for (Development Cooperation (NORAD), the United Kingdom Department for International Development (DFID), and the United States Agency for International Development (USAID). The full list of IAVI donors is available at http://www.iavi.org).
                Categories
                Articles

                Public health
                fisherfolk,truckers,hiv,substance use
                Public health
                fisherfolk, truckers, hiv, substance use

                Comments

                Comment on this article