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509
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
Authors:
Paul Bastard
,
Lindsey B. Rosen
,
Qian Zhang
…
Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years and account for ~ 20% of COVID-19 deaths
Authors:
Paul Bastard
,
Adrian. Gervais
,
Tom Le Voyer
…
Genetically diverse mouse models of SARS-CoV-2 infection reproduce clinical variation in type I interferon and cytokine responses in COVID-19
Authors:
Shelly J. Robertson
,
Olivia Bedard
,
Kristin L. McNally
…
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Steven M. Holland
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