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      Augmented Inverse Probability Weighting and the Double Robustness Property

      research-article
      Medical Decision Making
      SAGE Publications
      double robustness, propensity score, regression, simulation study

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          Abstract

          This article discusses the augmented inverse propensity weighted (AIPW) estimator as an estimator for average treatment effects. The AIPW combines both the properties of the regression-based estimator and the inverse probability weighted (IPW) estimator and is therefore a “doubly robust” method in that it requires only either the propensity or outcome model to be correctly specified but not both. Even though this estimator has been known for years, it is rarely used in practice. After explaining the estimator and proving the double robustness property, I conduct a simulation study to compare the AIPW efficiency with IPW and regression under different scenarios of misspecification. In 2 real-world examples, I provide a step-by-step guide on implementing the AIPW estimator in practice. I show that it is an easily usable method that extends the IPW to reduce variability and improve estimation accuracy.

          Highlights
          • • Average treatment effects are often estimated by regression or inverse probability weighting methods, but both are vulnerable to bias.

          • • The augmented inverse probability weighted estimator is an easy-to-use method for average treatment effects that can be less biased because of the double robustness property.

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          Most cited references33

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          Estimating causal effects of treatments in randomized and nonrandomized studies.

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            Nonparametric Estimation of Average Treatment Effects Under Exogeneity: A Review

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              Efficient Estimation of Average Treatment Effects Using the Estimated Propensity Score

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                Author and article information

                Contributors
                Journal
                Med Decis Making
                Med Decis Making
                MDM
                spmdm
                Medical Decision Making
                SAGE Publications (Sage CA: Los Angeles, CA )
                0272-989X
                1552-681X
                6 July 2021
                February 2022
                : 42
                : 2
                : 156-167
                Affiliations
                [1-0272989X211027181]Munich School of Management and Munich Center of Health Sciences, Ludwig-Maximilians-Universität Munich, Munich, Germany
                [2-0272989X211027181]Institute of Health Economics and Health Care Management, Helmholtz Zentrum München, Neuherberg, Germany
                Author notes
                [*]Munich School of Management and Munich Center of Health Sciences, Ludwig-Maximilians-Universität Munich, Geschwister-Scholl-Platz 1, 80539 Munich, Germany Email: kurz@ 123456bwl.lmu.de .

                There was a typo in the AIPW estimator equation on page 159 in the initial publication that has been corrected. For full details please see Corrigendum 10.1177/0272989X221075672.

                Article
                10.1177_0272989X211027181
                10.1177/0272989X211027181
                8793316
                34225519
                ff340805-bbe0-4d6d-9eae-6a9af57139eb
                © The Author(s) 2021

                This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License ( https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages ( https://us.sagepub.com/en-us/nam/open-access-at-sage).

                History
                : 1 December 2020
                : 27 May 2021
                Categories
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                Medicine
                double robustness,propensity score,regression,simulation study
                Medicine
                double robustness, propensity score, regression, simulation study

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