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      Defining normal ranges and centiles for heart and respiratory rates in infants and children: a cross-sectional study of patients attending an Australian tertiary hospital paediatric emergency department

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          Abstract

          Objective

          Key components in the assessment of a child in the emergency department (ED) are their heart and respiratory rates. In order to interpret these signs, practitioners must know what is normal for a particular age. The aim of this paper is to develop age-specific centiles for these parameters and to compare centiles with the previously published work of Fleming and Bonafide, and the Advanced Paediatric Life Support (APLS) reference ranges.

          Design

          A retrospective cross-sectional study.

          Setting

          The ED of the Children's Hospital at Westmead, Australia.

          Patients

          Afebrile, Triage Category 5 (low priority) patients aged 0–15 years attending the ED.

          Interventions

          Centiles were developed using quantile regression analysis, with cubic B-splines to model the centiles.

          Main outcome measures

          Centile charts were compared with previous studies by concurrently plotting the estimates.

          Results

          668 616 records were retrieved for ED attendances from 1995 to 2011, and 111 696 heart and respiratory rates were extracted for inclusion in the analysis. Graphical comparison demonstrates that with heart rate, our 50th centile agrees with the results of Bonafide, is considerably higher than the Fleming centiles and fits well between the APLS reference ranges. With respiratory rate, our 50th centile was considerably lower than the comparison centiles in infants, becomes higher with increasing age and crosses the lower APLS range in infants and upper range in teenagers.

          Conclusions

          Clinicians should consider adopting these centiles when assessing acutely unwell children. APLS should review their normal values for respiratory rate in infants and teenagers.

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          Most cited references12

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          Quantile regression methods for reference growth charts.

          Estimation of reference growth curves for children's height and weight has traditionally relied on normal theory to construct families of quantile curves based on samples from the reference population. Age-specific parametric transformation has been used to significantly broaden the applicability of these normal theory methods. Non-parametric quantile regression methods offer a complementary strategy for estimating conditional quantile functions. We compare estimated reference curves for height using the penalized likelihood approach of Cole and Green with quantile regression curves based on data used for modern Finnish reference charts. An advantage of the quantile regression approach is that it is relatively easy to incorporate prior growth and other covariates into the analysis of longitudinal growth data. Quantile specific autoregressive models for unequally spaced measurements are introduced and their application to diagnostic screening is illustrated.
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            Development of heart and respiratory rate percentile curves for hospitalized children.

            To develop and validate heart and respiratory rate percentile curves for hospitalized children and compare their vital sign distributions to textbook reference ranges and pediatric early warning score (EWS) parameters. For this cross-sectional study, we used 6 months of nurse-documented heart and respiratory rates from the electronic records of 14,014 children on general medical and surgical wards at 2 tertiary-care children's hospitals. We developed percentile curves using generalized additive models for location, scale, and shape with 67% of the patients and validated the curves with the remaining 33%. We then determined the proportion of observations that deviated from textbook reference ranges and EWS parameters. We used 116,383 heart rate and 116,383 respiratory rate values to develop and validate the percentile curves. Up to 54% of heart rate observations and up to 40% of respiratory rate observations in our sample were outside textbook reference ranges. Up to 38% of heart rate observations and up to 30% of respiratory rate observations in our sample would have resulted in increased EWSs. A high proportion of vital signs among hospitalized children would be considered out of range according to existing reference ranges and pediatric EWSs. The percentiles we derived may serve as useful references for clinicians and could be used to inform the development of evidence-based vital sign parameters for physiologic monitor alarms, inpatient electronic health record vital sign alerts, medical emergency team calling criteria, and EWSs.
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              • Record: found
              • Abstract: not found
              • Article: not found

              Revisions to the Canadian Triage and Acuity Scale paediatric guidelines (PaedCTAS).

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                Author and article information

                Journal
                Arch Dis Child
                Arch. Dis. Child
                archdischild
                adc
                Archives of Disease in Childhood
                BMJ Publishing Group (BMA House, Tavistock Square, London, WC1H 9JR )
                0003-9888
                1468-2044
                August 2015
                17 March 2015
                : 100
                : 8
                : 733-737
                Affiliations
                [1 ]Emergency Department, The Children's Hospital at Westmead , Westmead, New South Wales, Australia
                [2 ]Sydney Medical School, University of Sydney , Sydney, New South Wales, Australia
                [3 ]School of Public Health & Community Medicine, University of New South Wales , Sydney, New South Wales, Australia
                [4 ]The Women's and Children's Hospital , Adelaide, South Australia, Australia
                [5 ]Australian Catholic University , Sydney, New South Wales, Australia
                Author notes
                [Correspondence to ] A/Prof Fenton O'Leary, Emergency Department, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW 2145, Australia; fenton.oleary@ 123456health.nsw.gov.au
                Article
                archdischild-2014-307401
                10.1136/archdischild-2014-307401
                4518754
                25784747
                ff03757d-788d-4ab3-b0b4-756792ab22eb
                Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions

                This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

                History
                : 21 August 2014
                : 18 January 2015
                : 31 January 2015
                Categories
                1506
                Original Article
                Custom metadata
                unlocked

                Medicine
                accident & emergency,general paediatrics,physiology,resuscitation
                Medicine
                accident & emergency, general paediatrics, physiology, resuscitation

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