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      Critical incidents associated with pediatric anesthesia: changes over 6 years at a tertiary children’s hospital

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          Abstract

          Background

          Sustained interest is needed in the characteristics of critical incidents in pediatric anesthesia and related changes, for determining the causes and degree of potential harm; this will also improve the quality of medical care. This study aimed to analyze the incidence of critical incidents recorded in 2014–2019, and to compare them with those in 2008–2013.

          Methods

          Critical incidents associated with pediatric anesthesia, including cardiac arrest, recorded in a voluntary departmental reporting system between January 2014 and December 2019 were compared with those reported between January 2008 and August 2013 using chi-square test.

          Results

          We identified 295 (0.55%) critical incidents from 53,541 cases of pediatric anesthesia (3,471 cardiothoracic surgeries); this is consistent with the previously reported incidence of 0.46%. Among the critical incidents, the incidences of adverse events, sentinel event, near miss case and no-harm events were 93.9%, 1.7%, 0%, and 6.1% in 2014–2019, whereas those were 98.3%, 2.6%, 1.7%, and 0% in 2008–2013 (P = 0.023, 0.686, 0.080, and < 0.001, respectively). Cardiac arrest accounted for 25 (8.5%) cases of the 295 critical events, which significantly lower than that previously reported (18.3%; P = 0.020). Human factor-related events accounted for 61.0% of all critical incidences; this was similar to the previous data (58.5%).

          Conclusions

          Over six years, there has been no significant difference in the total incidence of critical events. Despite the decrease in the incidence of serious critical events, perioperative care in pediatric anesthesia can be further improved.

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          Most cited references18

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          Anesthesia-related cardiac arrest in children: update from the Pediatric Perioperative Cardiac Arrest Registry.

          The initial findings from the Pediatric Perioperative Cardiac Arrest (POCA) Registry (1994-1997) revealed that medication-related causes, often cardiovascular depression from halothane, were the most common. Changes in pediatric anesthesia practice may have altered the causes of cardiac arrest in anesthetized children. Nearly 80 North American institutions that provide anesthesia for children voluntarily enrolled in the Pediatric Perioperative Cardiac Arrest Registry. A standardized data form for each perioperative cardiac arrest in children
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            Anesthesia-related cardiac arrest in children: initial findings of the Pediatric Perioperative Cardiac Arrest (POCA) Registry.

            The Pediatric Perioperative Cardiac Arrest (POCA) Registry was formed in 1994 in an attempt to determine the clinical factors and outcomes associated with cardiac arrest in anesthetized children. Institutions that provide anesthesia for children are voluntarily enrolled in the POCA Registry. A representative from each institution provides annual institutional demographic information and submits anonymously a standardized data form for each cardiac arrest (defined as the need for chest compressions or as death) in anesthetized children 18 yr of age or younger. Causes and factors associated with cardiac arrest are analyzed. In the first 4 yr of the POCA Registry, 63 institutions enrolled and submitted 289 cases of cardiac arrest. Of these, 150 arrests were judged to be related to anesthesia. Cardiac arrest related to anesthesia had an incidence of 1.4 +/- 0.45 (mean +/- SD) per 10,000 instances of anesthesia and a mortality rate of 26%. Medication-related (37%) and cardiovascular (32%) causes of cardiac arrest were most common, together accounting for 69% of all arrests. Cardiovascular depression from halothane, alone or in combination with other drugs, was responsible for two thirds of all medication-related arrests. Thirty-three percent of the patients were American Society of Anesthesiologists physical status 1-2; in this group, 64% of arrests were medication-related, compared with 23% in American Society of Anesthesiologists physical status 3-5 patients (P < 0.01). Infants younger than 1 yr of age accounted for 55% of all anesthesia-related arrests. Multivariate analysis demonstrated two predictors of mortality: American Society of Anesthesiologists physical status 3-5 (odds ratio, 12.99; 95% confidence interval, 2.9-57.7), and emergency status (odds ratio, 3. 88; 95% confidence interval, 1.6-9.6). Anesthesia-related cardiac arrest occurred most often in patients younger than 1 yr of age and in patients with severe underlying disease. Patients in the latter group, as well as patients having emergency surgery, were most likely to have a fatal outcome. The identification of medication-related problems as the most frequent cause of anesthesia-related cardiac arrest has important implications for preventive strategies.
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              Human factors in preventing complications in anaesthesia: a systematic review

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                Author and article information

                Journal
                Anesth Pain Med (Seoul)
                Anesth Pain Med (Seoul)
                APM
                Anesthesia and Pain Medicine
                Korean Society of Anesthesiologists
                1975-5171
                2383-7977
                31 October 2022
                22 September 2022
                : 17
                : 4
                : 386-396
                Affiliations
                [1 ]Department of Anesthesiology and Pain Medicine, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea
                [2 ]Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
                Author notes
                Corresponding author: Jin-Tae Kim, M.D., Ph.D. Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul 03080, Korea Tel: 82-2-2072-3295, Fax: 82-2-747-8364 E-mail: jintae73@ 123456gmail.com

                Sung-Ae Cho and Ji-Hyun Lee contributed equally as the first author of this manuscript.

                Author information
                http://orcid.org/0000-0002-1519-3787
                http://orcid.org/0000-0002-8384-8191
                http://orcid.org/0000-0001-6736-4464
                http://orcid.org/0000-0002-7511-4104
                http://orcid.org/0000-0003-0697-1935
                http://orcid.org/0000-0002-2661-7944
                http://orcid.org/0000-0002-3738-0081
                Article
                apm-22164
                10.17085/apm.22164
                9663956
                36317431
                f4e27df5-aad2-4df4-ac0e-6c19ba018647
                Copyright © the Korean Society of Anesthesiologists, 2022

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 4 April 2022
                : 16 July 2022
                : 25 July 2022
                Categories
                Pediatric Anesthesia
                Clinical Research

                anesthesia,child,incident reportings,intraoperative complications,medical errors,perioperative care

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