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      Different phases of ATS use call for different interventions: a large qualitative study in Europe

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          Abstract

          Background

          Amphetamine-type stimulants (ATS) are globally widely used. Scientific literature generally defines four phases of substance use (initiation, continuation, increase and decrease); however, there is limited understanding of what influences these different phases of ATS use. The ATTUNE study investigated which factors shape individual phases of use, or ATS use patterns. In this article, we report on these phases into and out of ATS use, and propose a set of recommendations for prevention, harm reduction and treatment of the different phases of ATS use.

          Methods

          Qualitative, semi-structured interviews ( n = 237) were conducted in five different European countries with participants who had used ATS, varying from a few times in a lifetime to daily.

          Results

          Amphetamine and MDMA were the most commonly used ATS. Yet, types of ATS used differed between the countries. We found that people who use ATS have various motives for and dynamic patterns of ATS use with alternating phases of increase, continuation, decrease and sometimes dependence. Cessation was pursued in different ways and for diverse reasons, such as mental health problems and maturing out. Availability seemed not an issue, regardless of the type of ATS, phase or country.

          Conclusions

          These findings demonstrate that tailor-made interventions are needed for the diverse types of people who use ATS and different phases or patterns of ATS use, to reduce possible harms of use. We recommended a set of interventions for the different ATS phases. These include drug checking services, peer-led information, self-management of ATS use, mental health support to help people cope with stressful life events and prevent uncontrolled use, and follow-up support after treatment.

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          Most cited references64

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          The Severity of Dependence Scale (SDS): psychometric properties of the SDS in English and Australian samples of heroin, cocaine and amphetamine users

          The Severity of Dependence Scale (SDS) was devised to provide a short, easily administered scale which can be used to measure the degree of dependence experienced by users of different types of drugs. The SDS contains five items, all of which are explicitly concerned with psychological components of dependence. These items are specifically concerned with impaired control over drug taking and with preoccupation and anxieties about drug use. The SDS was given to five samples of drug users in London and Sydney. The samples comprised users of heroin and users of cocaine in London, and users of amphetamines and methadone maintenance patients in Sydney. The SDS satisfies a number of criteria which indicate its suitability as a measure of dependence. All SDS items load significantly with a single factor, and the total SDS score was extremely highly correlated with the single factor score. The SDS score is related to behavioural patterns of drug taking that are, in themselves, indicators of dependence, such as dose, frequency of use, duration of use, daily use and degree of contact with other drug users; it also shows criterion validity in that drug users who have sought treatment at specialist and non-specialist agencies for drug problems have higher SDS scores than non-treatment samples. The psychometric properties of the scale were good in all five samples, despite being applied to primary users of different classes of drug, using different recruitment procedures in different cities in different countries.
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            Responding to global stimulant use: challenges and opportunities

            We did a global review to synthesise data on the prevalence, harms, and interventions for stimulant use, focusing specifically on the use of cocaine and amphetamines. Modelling estimated the effect of cocaine and amphetamine use on mortality, suicidality, and blood borne virus incidence. The estimated global prevalence of cocaine use was 0·4% and amphetamine use was 0·7%, with dependence affecting 16% of people who used cocaine and 11% of those who used amphetamine. Stimulant use was associated with elevated mortality, increased incidence of HIV and hepatitis C infection, poor mental health (suicidality, psychosis, depression, and violence), and increased risk of cardiovascular events. No effective pharmacotherapies are available that reduce stimulant use, and the available psychosocial interventions (except for contingency management) had a weak overall effect. Generic approaches can address mental health and blood borne virus infection risk if better tailored to mitigate the harms associated with stimulant use. Substantial and sustained investment is needed to develop more effective interventions to reduce stimulant use.
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              "Chemsex" and harm reduction need among gay men in South London.

              Chemsex is a colloquial term used by gay men in some parts of the UK to describe the use of psychoactive substances (typically mephedrone, GHB/GBL or crystal methamphetamine) during sex. Use of these drugs by gay men in London appears to have risen sharply from relatively low levels and, as yet, there is little data to inform appropriate harm reduction services. This study sought to understand the personal and social context of chemsex and the nature of harm reduction need.
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                Author and article information

                Contributors
                nienkeliebregts@gmail.com
                rrigoni@correlation-net.org
                benjamin.petruzelka@lf1.cuni.cz
                Miroslav.bartak@lf1.cuni.cz
                mrowicka@aps.edu.pl
                zurhold@uke.de
                kschiffer@correlation-net.org
                Journal
                Harm Reduct J
                Harm Reduct J
                Harm Reduction Journal
                BioMed Central (London )
                1477-7517
                12 April 2022
                12 April 2022
                2022
                : 19
                : 36
                Affiliations
                [1 ]Correlation-European Harm Reduction Network, Amsterdam, The Netherlands
                [2 ]GRID grid.4491.8, ISNI 0000 0004 1937 116X, Department of Addictology, First Faculty of Medicine, , Charles University, ; Prague, Czech Republic
                [3 ]GRID grid.445465.2, ISNI 0000 0004 0621 398X, Institute of Psychology, , Maria Grzegorzewska University, ; Warsaw, Poland
                [4 ]GRID grid.13648.38, ISNI 0000 0001 2180 3484, Centre of Interdisciplinary Addiction Research of Hamburg University (ZIS), Department of Psychiatry, , University Medical Centre Hamburg-Eppendorf, ; Hamburg, Germany
                [5 ]GRID grid.7177.6, ISNI 0000000084992262, Bonger Institute of Criminology, , University of Amsterdam, ; Amsterdam, The Netherlands
                Author information
                http://orcid.org/0000-0001-5929-147X
                Article
                617
                10.1186/s12954-022-00617-5
                9004030
                35413972
                ed22ebf6-36b2-4042-bf0a-0bad4b48f836
                © The Author(s) 2022

                Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

                History
                : 13 September 2021
                : 28 March 2022
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100001826, ZonMw;
                Award ID: 63200000103
                Funded by: National Institute for Health Research (NIHR)
                Award ID: PR-ST-0416-10001
                Funded by: Federal Ministry of Health
                Award ID: ZMVI1-2516DSM222
                Funded by: Government Council for Drug Policy Coordination and the institutional support Progress
                Award ID: Q06/LF1
                Funded by: National Bureau for Drug Prevention
                Categories
                Research
                Custom metadata
                © The Author(s) 2022

                Health & Social care
                ats use phases,policy,practice,qualitative research,prevention,stimulants
                Health & Social care
                ats use phases, policy, practice, qualitative research, prevention, stimulants

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