contributors
Dr. Vinita Chauhan
, is a Research Scientist at the Consumer and Clinical Radiation Protection Bureau
of Health Canada. She is a Canadian Delegate on the High-Level Group on Low Dose Research
and Extended Advisory Group on Molecular Screening and Toxicogenomics of the Organisation
for Economic Cooperation and Development.
Dr. Chris Barber
is the CEO of Lhasa Limited, an educational not-forprofit charity that supports its
members through the collaborative datasharing and the development of expert and machine-learning
in silico predictive systems.
Dr. Crina Heghes
is a Principal Global Alliance Manager at Lhasa. She is currently leading Kaptis,
strategic work dedicated to the development of a framework to support risk assessment
and decision-making in toxicology using a combination of knowledge and assay data
in the context of adverse outcome pathways.
Dr. Carole Yauk
is a Professor in the Department of Biology, University of Ottawa, where she holds
the Canada Research Chair in Genomics and the Environment. Dr. Yauk serves as a Canadian
delegate to the OECD’s Extended Advisory Group on Molecular Screening and Toxicogenomics.
Within this group, she contributed to the development of the AOP Users’ Handbook and
is an AOP developer and reviewer.
Dr. Francesco Marchetti
is a Research Scientist at Health Canada and an internationally recognized expert
in germ-cell mutagenesis and genetic toxicology. His current research focuses on using
new genomics tools to advance the study of germ cell mutagenesis and the implementation
of the Adverse Outcome Pathway approach to characterize the mechanisms leading the
genetic toxicity outcomes.
Dr. Daniel Villeneuve
is a Research Toxicologist with the US Environmental Protection Agency. He serves
as a delegate to the OECD’s Extended Advisory Group on Molecular Screening and Toxicogenomics.
Dr. Donald Cool
is a Technical Executive with Electrical Power Research Institute, Charlotte, NC.
He is a member of the Main Commission of the International Commission on Radiological
Protection (ICRP), Chair of ICRP Committee 4 on Applications, and a Council Member
of the U.S. National Council on Radiation Protection and Measurements.
Dr. Dominique Laurier
is a Radiation Epidemiologist, Chair of the High-Level Group on Low Dose Research
(HLG-LDR) of the Nuclear Energy Agency (NEA), Member of the Main Commission of the
International Commission on Radiological protection (ICRP), Member of the French delegation
at the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR).
Dr. Jason O’Brien
specializes in developing and applying modern molecular and high-throughput technologies,
such as genomics and in vitro models, for characterizing the toxicological hazard
of ecological pollutants. O’Brien works with Canadian and International regulators
to promote and facilitate the incorporation of modern molecular toxicology data into
the chemical risk assessment process.
Dr. Betty Meek
, University of Ottawa, previously managed several chemical risk assessment programmes
within Health Canada. With colleagues internationally, she has contributed to or led
initiatives in evolving methodology in chemical risk assessment.
Dr. Holly Laakso
is a Biologist in the Radiobiology & Health Branch at Canadian Nuclear Laboratories.
Her current research focuses on the effects of low dose radiation on biological systems.
Dr. Nathalie Delrue
holds a Doctorate degree in pharmaceutical sciences from University René Descartes
(Paris V). She is an Administrator of the Test Guidelines Programme at the Organisation
for Economic Co-operation and Development (OECD); she is also in charge of the coordination
of the Adverse Outcome Pathway development programme, initiated at OECD in 2012.
Dr. Magdalini Sachana
holds a Doctorate degree and is a Policy Analyst with Organisation for Economic Co-operation
and Development (OECD). She is also in charge of the coordination of the Adverse Outcome
Pathway development programme, initiated at OECD in 2012.
Julie Burtt
is a Radiation Biologist with the Canadian Nuclear Safety Commission. Her research
is focused on the potential health effects from exposure to low doses of ionizing
radiation. She is an advisor of the United Nations Scientific Committee on the Effects
of Atomic Radiation (UNSCEAR).
Dr. Julie LeBlanc
is a Radiation Biologist with the Canadian Nuclear Safety Commission. Her research
is focused on the potential health effects from exposure to low doses of ionizing
radiation.
Dr. Ruth C. Wilkins
is the Division Chief of the Ionizing Health Sciences Division at Health Canada.
She is an alternate representative of the United Nations Scientific Committee on the
Effects of Atomic Radiation (UNSCEAR).
Dr. Danielle Beaton
is a Research Scientist with Canadian Nuclear Laboratories. Her current research
focuses on the effects of low dose radiation on biological systems.
Dr. Sabina Halappanava
is a research Scientist with the Genomics and Nanotoxicology Laboratory of the Mechanistic
Studies Division, Health Canada. She serves as a Canadian delegate to the OECD’s Extended
Advisory Group on Molecular Screening and Toxicogenomics. She has developed AOP 173
for lung fibrosis. Her current research focuses on elucidating mechanisms of lung
toxicity induced by nanomaterials and developing animal alternatives to predicting
inhalation toxicity of nanomaterials.
Dr. Tara Barton-Maclaren
is a Research Manager at the Healthy Environments and Consumer Safety Branch of Health
Canada. She serves as a Canadian delegate to the OECD’s Extended Advisory Group on
Molecular Screening and Toxicogenomics.
Michael Boyd
is the director of the U.S. EPA Radiation Protection Division’s Center for Science
ane is a member of the NCRP, ICRP Committee 4 and chaired the OECD/Nuclear Energy
Agency’s Committee on Radiological Protection and Public Health from 2015 until September
2020.
Dr. Catalina Anghel
is a Computational Research Scientist and Section Head of Codes and Algorithms at
the Canadian Nuclear Laboratories.
Dr. Edward J. Perkins
currently serves as the Acting Army Deputy Chief Scientist and Army Senior Research
Scientist in Environmental Networks and Genetic Toxicology in Environmental Laboratory
at the U.S. Corps Engineers Army Engineer Research and Development Center.
Dr. Edward Lazo
holds a PhD in radiological protection, and Master’s and Bachelor’s degrees in nuclear
engineering. His 30-year career has focused on practical, operational experience,
and policy, regulatory and implementational application of lessons learned.
Dr. Maurice Whelan
is head of the Chemical Safety and Alternative Methods Unit of the European Commission’s
Joint Research Center. He is also head of the European Union Reference Laboratory
for alternatives to animal testing (EURL ECVAM) and co-chair of the Extended Advisory
Group for Molecular Screening and Toxicogenomics at the OECD that manages its Adverse
Outcome Pathway Programme.
Dr. Russell Thomas
is the director of the Center for Computational Toxicology and Exposure in the Office
of Research and Development of the U.S. Environmental Protection Agency and co-chair
of the Extended Advisory Group for Molecular Screening and Toxicogenomics at the OECD.
