Xanthogranulomatous oophoritis is a benign chronic inflammation causing massive destruction of involved organs. The disease is characterized by the infiltration of lipid-laden histiocytes or xanthoma cells along with giant cells, lymphocytes, and neutrophils. Diagnosis is often difficult as signs and symptoms are nonspecific and definitive evidence comes from histopathology.
We report a case of 27-year-old female presenting with infertility and an adnexal mass. Intraoperatively on laparoscopy, it was an ovarian abscess. Later on, through histopathology, it was diagnosed as xanthogranulomatous oophoritis.
Xanthogranulomatous inflammation in the ovaries is very rare, and when present, it can be a diagnostic challenge. The disease can mimic both benign and malignant ovarian masses, as such high degree of clinical suspicion combined with histopathology can aid in establishing the diagnosis.