High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study.

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Abstract

Abdominoperineal resection is the standard treatment for patients with distal T2 or T3 rectal cancers; however, the procedure is extensive and mutilating, and alternative treatment strategies are being investigated. We did a prospective observational trial to assess whether high-dose radiotherapy with concomitant chemotherapy followed by observation (watchful waiting) was successful for non-surgical management of low rectal cancer.

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Journal

Journal ID (iso-abbrev): Lancet Oncol.

Title: The Lancet. Oncology

ISSN (Electronic): 1474-5488

ISSN (Print): 1470-2045

Publication date (Electronic): Aug 2015

Volume: 16

Issue: 8

Affiliations

[1 ] Danish Colorectal Cancer Center South, Vejle Hospital, Vejle, Denmark; Department of Oncology, Section of Radiotherapy, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. Electronic address: ane.lindegaard.appelt@rsyd.dk.

[2 ] Danish Colorectal Cancer Center South, Vejle Hospital, Vejle, Denmark.

[3 ] Digestive Disease Center, Bispebjerg University Hospital, Copenhagen, Denmark.

[4 ] Department of Surgery, Aalborg University Hospital, Aalborg, Denmark.

Article

Publisher Item ID: S1470-2045(15)00120-5

DOI: 10.1016/S1470-2045(15)00120-5

PubMed ID: 26156652

SO-VID: e40a8ba9-cebd-417b-9fca-2d21273934ed

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