- Record: found
- Abstract: not found
- Article: not found
Efficacy and safety of a monthly buprenorphine depot injection for opioid use disorder: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
Barbara R Haight ,
Susan M Learned ,
Celine M Laffont ,
Paul J Fudala ,
Yue Zhao ,
Amanda S Garofalo ,
Mark K Greenwald ,
Vijay R Nadipelli ,
Walter Ling ,
Christian Heidbreder ,
James L. Andersen ,
Genie L. Bailey ,
Scott Robert Bartley ,
Michael J. Biunno ,
Brent Boyett ,
Jesse M. Carr ,
Eduardo Cifuentes ,
Sandra Daniela Duarte-Sckell ,
Otto R. Dueno ,
Boyde J. Harrison ,
David R. Hassman ,
Kent Steven Hoffman ,
Valentin Isacesu ,
Saleem Ishaque ,
Rishi Kakar ,
Kyle Kampman ,
Richard D. Knapp ,
George Konis ,
Jelena Kunovac ,
Joseph A. Kwentus ,
Lawrence S. Levinson ,
Shishuka Malhotra ,
Vishaal Mehra ,
Ricky Stuart Mofsen ,
Marvin Lane Peyton ,
Gita G. Pujari ,
Rakesh Ranjan ,
Daniel Rutrick ,
Gregory Seal ,
Scott Daniel Segal ,
Rajinder Shiwach ,
Haydn Mikel Thomas ,
Peter Paul Ventre ,
Amit K. Vijapura ,
David P. Walling ,
Katharina L. Wiest
February 2019
February 2019
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
RBP-6000, referred to as BUP-XR (extended-release buprenorphine), is a subcutaneously
injected, monthly buprenorphine treatment for opioid use disorder. BUP-XR provides
sustained buprenorphine plasma concentrations to block drug-liking of abused opioids
over the entire monthly dosing period, while controlling withdrawal and craving symptoms.
Administration of BUP-XR in a health-care setting also mitigates abuse, misuse, diversion,
and unintentional exposure. We aimed to investigate the efficacy of different BUP-XR
dosing regimens in participants with opioid use disorder.
Related collections
Author and article information
Comments
Comment on this article
scite_
0
0
0
0
Smart Citations0
0
0
0
Citing PublicationsSupportingMentioningContrasting
See how this article has been cited at scite.ai
scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.