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      The 12-Item General Health Questionnaire as an Effective Mental Health Screening Tool for General Korean Adult Population

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          Abstract

          Objective

          The 12-item General Health Questionnaire (GHQ-12) has been used extensively in various settings across different cultures. This study was conducted to determine the thresholds associated with optimum sensitivity and specificity for the GHQ-12 in Korean adults.

          Methods

          Data was acquired from a sample of 6,510 Korean adults, ages 18 to 64 years old, who were selected from the 2005 Census (2,581 men and 3,929 women). Participants completed the GHQ-12 and the Korean Composite International Diagnostic Interview (K-CIDI). Receiver Operating Characteristic (ROC) curve analysis was conducted.

          Results

          The mean GHQ-12 score for the total sample was 1.63 (SD 1.98). The internal consistency of the GHQ-12 was good (Cronbach's α=0.72). Results from the ROC curve indicated that the GHQ-12 yielded greater accuracy when identifying mood and anxiety disorders than when identifying all mental disorders as a whole. The optimal threshold of the GHQ-12 was either 1/2 or 2/3 point depending on the disorder, but was mainly 2/3.

          Conclusion

          The Korean version of the GHQ-12 could be used to screen for individuals at high risk of mental disorders, namely mood and anxiety disorders.

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          Most cited references39

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          Diagnostic and statistical manual of mental disorders.

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            Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine.

            The clinical performance of a laboratory test can be described in terms of diagnostic accuracy, or the ability to correctly classify subjects into clinically relevant subgroups. Diagnostic accuracy refers to the quality of the information provided by the classification device and should be distinguished from the usefulness, or actual practical value, of the information. Receiver-operating characteristic (ROC) plots provide a pure index of accuracy by demonstrating the limits of a test's ability to discriminate between alternative states of health over the complete spectrum of operating conditions. Furthermore, ROC plots occupy a central or unifying position in the process of assessing and using diagnostic tools. Once the plot is generated, a user can readily go on to many other activities such as performing quantitative ROC analysis and comparisons of tests, using likelihood ratio to revise the probability of disease in individual subjects, selecting decision thresholds, using logistic-regression analysis, using discriminant-function analysis, or incorporating the tool into a clinical strategy by using decision analysis.
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              Measuring the accuracy of diagnostic systems.

              J Swets (1988)
              Diagnostic systems of several kinds are used to distinguish between two classes of events, essentially "signals" and "noise". For them, analysis in terms of the "relative operating characteristic" of signal detection theory provides a precise and valid measure of diagnostic accuracy. It is the only measure available that is uninfluenced by decision biases and prior probabilities, and it places the performances of diverse systems on a common, easily interpreted scale. Representative values of this measure are reported here for systems in medical imaging, materials testing, weather forecasting, information retrieval, polygraph lie detection, and aptitude testing. Though the measure itself is sound, the values obtained from tests of diagnostic systems often require qualification because the test data on which they are based are of unsure quality. A common set of problems in testing is faced in all fields. How well these problems are handled, or can be handled in a given field, determines the degree of confidence that can be placed in a measured value of accuracy. Some fields fare much better than others.
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                Author and article information

                Journal
                Psychiatry Investig
                Psychiatry Investig
                PI
                Psychiatry Investigation
                Korean Neuropsychiatric Association
                1738-3684
                1976-3026
                December 2013
                16 December 2013
                : 10
                : 4
                : 352-358
                Affiliations
                [1 ]Department of Psychiatry, Kangwon National University School of Medicine, Chuncheon, Republic of Korea.
                [2 ]Department of Psychiatry and Behavioral Science, Seoul National University College of Medicine, Seoul, Republic of Korea.
                [3 ]Department of Psychiatry, Asan Medical Center, Ulsan University College of Medicine, Seoul, Republic of Korea.
                [4 ]Department of Psychiatry, College of Medicine, Inha University, Incheon, Republic of Korea.
                [5 ]Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
                [6 ]Department of Psychiatry, Kyungpook National University College of Medicine, Daegu, Republic of Korea.
                [7 ]Department of Psychiatry, Seoul Medical Center, Seoul, Republic of Korea.
                Author notes
                Correspondence: Jong-Ik Park, MD, PhD, LLM. Department of Psychiatry, Kangwon National University School of Medicine, 156 Baengnyeong-ro, Chuncheon 200-722, Republic of Korea. Tel: +82-33-258-9171, Fax: +82-33-257-4656, lugar@ 123456kangwon.ac.kr
                Article
                10.4306/pi.2013.10.4.352
                3902152
                24474983
                dfa9f693-5a60-42a0-92c8-9a79b087a544
                Copyright © 2013 Korean Neuropsychiatric Association

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 21 November 2012
                : 21 February 2013
                : 27 February 2013
                Funding
                Funded by: Korean Ministry of Health and Welfare
                Categories
                Original Article

                Clinical Psychology & Psychiatry
                psychiatric diagnoses,sensitivity,ghq-12,specificity,optimal threshold

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