Effect of an Inactivated Vaccine Against SARS-CoV-2 on Safety and Immunogenicity Outcomes: Interim Analysis of 2 Randomized Clinical Trials

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Abstract

<p class="first" id="d5333932e400">A vaccine against coronavirus disease 2019 (COVID-19) is urgently needed.</p>

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Author and article information

Journal

Title: JAMA

Abbreviated Title: JAMA

Publisher: American Medical Association (AMA)

ISSN (Print): 0098-7484

Publication date (Electronic): August 13 2020

Affiliations

[1 ]Henan Center for Disease Control and Prevention, Zhengzhou, Henan, China

[2 ]National Engineering Technology Research Center for Combined Vaccines, Wuhan Institute of Biological Products Co Ltd, Wuhan, Hubei, China

[3 ]China National Biotec Group Company Limited, Beijing, China

[4 ]Chinese Academy of Sciences Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, China

[5 ]Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health and State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China

[6 ]Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, China

[7 ]National Medical Center for Major Public Health Events, Huazhong University of Science and Technology, Wuhan, Hubei, China

Article

DOI: 10.1001/jama.2020.15543

PMC ID: 7426884

PubMed ID: 32789505

SO-VID: dedaf3d5-2ab2-480f-8f4a-b39dbed2cc0c

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Effect of an Inactivated Vaccine Against SARS-CoV-2 on Safety and Immunogenicity Outcomes : Interim Analysis of 2 Randomized Clinical Trials

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