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      Safety of sodium-glucose co-transporter-2 inhibitors on amputation across categories of baseline cardiovascular disease and diuretics use in patients with type 2 diabetes.

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          Abstract

          To assess the risk of amputation associated with sodium-glucose co-transporter-2 inhibitors (SGLT2is) among patients with type 2 diabetes, across categories of baseline cardiovascular disease (CVD) and diuretic use (DU).

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          Author and article information

          Journal
          Diabetes Obes Metab
          Diabetes, obesity & metabolism
          Wiley
          1463-1326
          1462-8902
          Nov 2023
          : 25
          : 11
          Affiliations
          [1 ] School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
          [2 ] Research Department of Practice and Policy, UCL School of Pharmacy, London, UK.
          [3 ] Department of Biohealth Regulatory Science, Sungkyunkwan University, Suwon, Republic of Korea.
          [4 ] Centre for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec, Canada.
          [5 ] Division of Endocrinology and Metabolism, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.
          [6 ] Department of Internal Medicine Seoul National University College of Medicine, Seoul, South Korea.
          [7 ] Department of Translational Medicine, Seoul National University College of Medicine, Seoul, South Korea.
          [8 ] Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.
          [9 ] Institute on Aging, Seoul National University, Seoul, South Korea.
          [10 ] Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Republic of Korea.
          [11 ] Centre for Medicines Optimisation Research and Education, University College London Hospitals NHS Foundation Trust, London, UK.
          [12 ] Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, University of Hong Kong, Hong Kong, Hong Kong.
          [13 ] Department of Clinical Research Design & Evaluation, Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University, Seoul, Republic of Korea.
          Article
          10.1111/dom.15221
          37503763
          de66f710-03f4-4368-88d5-2f8ce8b914d1
          History

          type 2 diabetes,cardiovascular disease,diuretics,amputation,SGLT2 inhibitors

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