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      Safe Artificial General Intelligence via Distributed Ledger Technology

       
      Big Data and Cognitive Computing
      MDPI AG

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          Abstract

          Artificial general intelligence (AGI) progression metrics indicate AGI will occur within decades. No proof exists that AGI will benefit humans and not harm or eliminate humans. A set of logically distinct conceptual components is proposed that are necessary and sufficient to (1) ensure various AGI scenarios will not harm humanity, and (2) robustly align AGI and human values and goals. By systematically addressing pathways to malevolent AI we can induce the methods/axioms required to redress them. Distributed ledger technology (DLT, “blockchain”) is integral to this proposal, e.g., “smart contracts” are necessary to address the evolution of AI that will be too fast for human monitoring and intervention. The proposed axioms: (1) Access to technology by market license. (2) Transparent ethics embodied in DLT. (3) Morality encrypted via DLT. (4) Behavior control structure with values at roots. (5) Individual bar-code identification of critical components. (6) Configuration Item (from business continuity/disaster recovery planning). (7) Identity verification secured via DLT. (8) “Smart” automated contracts based on DLT. (9) Decentralized applications—AI software modules encrypted via DLT. (10) Audit trail of component usage stored via DLT. (11) Social ostracism (denial of resources) augmented by DLT petitions. (12) Game theory and mechanism design.

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          Most cited references36

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          Mastering the game of Go with deep neural networks and tree search.

          The game of Go has long been viewed as the most challenging of classic games for artificial intelligence owing to its enormous search space and the difficulty of evaluating board positions and moves. Here we introduce a new approach to computer Go that uses 'value networks' to evaluate board positions and 'policy networks' to select moves. These deep neural networks are trained by a novel combination of supervised learning from human expert games, and reinforcement learning from games of self-play. Without any lookahead search, the neural networks play Go at the level of state-of-the-art Monte Carlo tree search programs that simulate thousands of random games of self-play. We also introduce a new search algorithm that combines Monte Carlo simulation with value and policy networks. Using this search algorithm, our program AlphaGo achieved a 99.8% winning rate against other Go programs, and defeated the human European Go champion by 5 games to 0. This is the first time that a computer program has defeated a human professional player in the full-sized game of Go, a feat previously thought to be at least a decade away.
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            Drug Resistance in Cancer: An Overview

            Cancers have the ability to develop resistance to traditional therapies, and the increasing prevalence of these drug resistant cancers necessitates further research and treatment development. This paper outlines the current knowledge of mechanisms that promote or enable drug resistance, such as drug inactivation, drug target alteration, drug efflux, DNA damage repair, cell death inhibition, and the epithelial-mesenchymal transition, as well as how inherent tumor cell heterogeneity plays a role in drug resistance. It also describes the epigenetic modifications that can induce drug resistance and considers how such epigenetic factors may contribute to the development of cancer progenitor cells, which are not killed by conventional cancer therapies. Lastly, this review concludes with a discussion on the best treatment options for existing drug resistant cancers, ways to prevent the formation of drug resistant cancers and cancer progenitor cells, and future directions of study.
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              Blockchains and Smart Contracts for the Internet of Things

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                Author and article information

                Contributors
                (View ORCID Profile)
                Journal
                BDCCAG
                Big Data and Cognitive Computing
                BDCC
                MDPI AG
                2504-2289
                September 2019
                July 08 2019
                : 3
                : 3
                : 40
                Article
                10.3390/bdcc3030040
                d8e7c888-c2f0-407d-93b9-539834f0bbce
                © 2019

                https://creativecommons.org/licenses/by/4.0/

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