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      Recent Advances in Silver nanozymes: Concept, Mechanism, and Applications in Detection

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          Abstract

          Natural enzymes accelerate substrate‐specific reactions making them of exquisite interest for various applications. However, their appeal is lost in a practical setting due to low stability and high preparation expenses. This is the primary reason behind the flourishing in the research of nanozyme, i.e., artificial enzymes, in the past decade. Their unique physicochemical properties make them a promising candidate for various applications, especially in diagnostics and detection. They possess an enzyme‐like activity and can overcome the drawbacks of natural protein‐based enzymes. Nanozymes are nanomaterials that show enzyme‐like catalytic activity and have great potential to replace natural enzymes for industrial applications. The scope of tuning these nanozymes enhances their catalytic activity and provides specificity, benefiting disease diagnosis and drug delivery. This review aims to report the applications of silver nanozymes in disease diagnosis, glucose detection, and cancer therapy. Their role in detecting heavy metal ions for environmental safety has also been highlighted.

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          Most cited references229

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          Structural absorption by barbule microstructures of super black bird of paradise feathers

          Many studies have shown how pigments and internal nanostructures generate color in nature. External surface structures can also influence appearance, such as by causing multiple scattering of light (structural absorption) to produce a velvety, super black appearance. Here we show that feathers from five species of birds of paradise (Aves: Paradisaeidae) structurally absorb incident light to produce extremely low-reflectance, super black plumages. Directional reflectance of these feathers (0.05–0.31%) approaches that of man-made ultra-absorbent materials. SEM, nano-CT, and ray-tracing simulations show that super black feathers have titled arrays of highly modified barbules, which cause more multiple scattering, resulting in more structural absorption, than normal black feathers. Super black feathers have an extreme directional reflectance bias and appear darkest when viewed from the distal direction. We hypothesize that structurally absorbing, super black plumage evolved through sensory bias to enhance the perceived brilliance of adjacent color patches during courtship display.
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            Intrinsic peroxidase-like activity of ferromagnetic nanoparticles.

            Nanoparticles containing magnetic materials, such as magnetite (Fe3O4), are particularly useful for imaging and separation techniques. As these nanoparticles are generally considered to be biologically and chemically inert, they are typically coated with metal catalysts, antibodies or enzymes to increase their functionality as separation agents. Here, we report that magnetite nanoparticles in fact possess an intrinsic enzyme mimetic activity similar to that found in natural peroxidases, which are widely used to oxidize organic substrates in the treatment of wastewater or as detection tools. Based on this finding, we have developed a novel immunoassay in which antibody-modified magnetite nanoparticles provide three functions: capture, separation and detection. The stability, ease of production and versatility of these nanoparticles makes them a powerful tool for a wide range of potential applications in medicine, biotechnology and environmental chemistry.
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              Graphene: status and prospects.

              A. K. Geim (2009)
              Graphene is a wonder material with many superlatives to its name. It is the thinnest known material in the universe and the strongest ever measured. Its charge carriers exhibit giant intrinsic mobility, have zero effective mass, and can travel for micrometers without scattering at room temperature. Graphene can sustain current densities six orders of magnitude higher than that of copper, shows record thermal conductivity and stiffness, is impermeable to gases, and reconciles such conflicting qualities as brittleness and ductility. Electron transport in graphene is described by a Dirac-like equation, which allows the investigation of relativistic quantum phenomena in a benchtop experiment. This review analyzes recent trends in graphene research and applications, and attempts to identify future directions in which the field is likely to develop.
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                Author and article information

                Contributors
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                Journal
                Advanced Materials Interfaces
                Adv Materials Inter
                Wiley
                2196-7350
                2196-7350
                October 2022
                September 04 2022
                October 2022
                : 9
                : 30
                Affiliations
                [1 ] Amity Institute of Nanotechnology Amity University Uttar Pradesh, Sector 125 Noida 201303 India
                [2 ] The University of Queensland School of Dentistry Oral Health Centre Herston 288 Herston Road Herston QLD 4006 Australia
                [3 ] Department of Chemical and Materials Engineering King Abdulaziz University Jeddah 21589 Saudi Arabia
                [4 ] Department of Nanotechnology University of Kashmir Hazratbal Srinagar Jammu and Kashmir 190006 India
                Article
                10.1002/admi.202200928
                d8541e5b-20fb-4306-93f3-7e96f5553d62
                © 2022

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