The purpose of the study was to establish normative data on the mesiodistal crown dimensions of Americans of Dominican background. The Bolton tooth size analysis was performed on a sample of 54 Dominican Americans. The mean, range and standard deviation were calculated for the size of the teeth, and a coefficient of variation was obtained for the tooth size ratio. A 2-sample t-test was used to test for the statistical difference between means. In general, the values obtained for the Dominican American sample closely resembled previous data available for the African American population. The tooth size ratios obtained were compared to the Bolton ratios. The overall ratio was found to be 91.3, equivalent to the Bolton overall ratio, whereas the anterior ratio was 78.1, larger than the 77.1 Bolton ratio. The frequency of tooth size discrepancy outside 2 standard deviations from the Bolton mean was also calculated. An overall tooth size discrepancy was found in 11% of our sample, and 28% of the sample presented an anterior tooth size discrepancy.