Continuous process technology: a tool for sustainable production

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Novel process windows for enabling, accelerating, and uplifting flow chemistry.

Jason Noel, Qi Wang, D Kralisch … (2013)

Novel Process Windows make use of process conditions that are far from conventional practices. This involves the use of high temperatures, high pressures, high concentrations (solvent-free), new chemical transformations, explosive conditions, and process simplification and integration to boost synthetic chemistry on both the laboratory and production scale. Such harsh reaction conditions can be safely reached in microstructured reactors due to their excellent transport intensification properties. This Review discusses the different routes towards Novel Process Windows and provides several examples for each route grouped into different classes of chemical and process-design intensification. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Continuous flow reactors: a perspective

Charlotte Wiles, Paul Watts (2012)

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Applying flow chemistry: methods, materials, and multistep synthesis.

D McQuade, Peter H. Seeberger (2013)

The synthesis of complex molecules requires control over both chemical reactivity and reaction conditions. While reactivity drives the majority of chemical discovery, advances in reaction condition control have accelerated method development/discovery. Recent tools include automated synthesizers and flow reactors. In this Synopsis, we describe how flow reactors have enabled chemical advances in our groups in the areas of single-stage reactions, materials synthesis, and multistep reactions. In each section, we detail the lessons learned and propose future directions.

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Author and article information

Journal

Journal ID (publisher-id): GRCHFJ

Title: Green Chem.

Abbreviated Title: Green Chem.

Publisher: Royal Society of Chemistry (RSC)

ISSN (Print): 1463-9262

ISSN (Electronic): 1463-9270

Publication date Created: 2014

Publication date (Print): 2014

Volume: 16

Issue: 1

Pages: 55-62

Article

DOI: 10.1039/C3GC41797B

SO-VID: d112e85f-0191-423b-8b6c-9d36b18b548e

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