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      Disfunções orofaciais em pacientes infantojuvenis com leucemia aguda Translated title: Orofacial dysfunctions in infants and young children with acute leukemia

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          Abstract

          RESUMO Objetivo Identificar a ocorrência de disfunções orofaciais em pacientes infantojuvenis com leucemia aguda, submetidos à quimioterapia de remissão. Métodos Em um período de 16 meses, 40 pacientes com leucemias agudas, entre 3 e 18 anos de idade, foram admitidos em um hemocentro no estado do Amazonas. Destes, 23 foram incluídos neste estudo transversal e submetidos à avaliação das funções orofaciais, por meio do Nordic Orofacial Test-Screening (NOT-S), entre o trigésimo (D30) e o trigésimo terceiro dia (D33) da fase de indução da remissão. A presença de manifestações orais também foi avaliada por meio de exame clínico. Resultados Disfunção orofacial foi observada em, aproximadamente, metade dos casos avaliados (n=11). Destes pacientes, todos tiveram o domínio Secura de Boca (VI) alterado e 81,8% (n=9) apresentaram alteração no domínio Mastigação e Deglutição (IV). Mucosites em lábios, língua, soalho e orofaringe foram as lesões orais mais encontradas após a fase de indução. Houve associação entre a ocorrência de lesões orais nos pacientes avaliados e a presença de disfunção orofacial, segundo o NOT-S (IC 95%, p-valor = 0,027). Conclusão Sugere-se que a disfunção orofacial seja frequente na fase de indução da remissão em pacientes infantojuvenis com leucemias agudas. Estudos sobre as disfunções orofaciais nessa população, bem como sua relação com as lesões orais são necessários para melhor esclarecimento e compreensão dos impactos funcionais.

          Translated abstract

          ABSTRACT Purpose To Identify the occurrence of orofacial dysfunctions in young children and adolescents with acute leukemia who are undergoing remission chemotherapy. Methods Over a period of 16 months, 40 three to eighteen year -old patients with acute leukemia were admitted to the Amazonas State Hemocenter. Of these, 23 were included in the cross-sectional study and submitted to the evaluation of orofacial functions using the Nordic Orofacial Test-Screening, between D30 and D33 of the remission induction phase. The presence of oral manifestations was also evaluated via clinical examination. Results Orofacial dysfunction was observed in approximately half of the evaluated cases (n=11). Of these patients, all had alterations in the Dryness of the Mouth (VI) domain and 81.8% (n=9) showed alterations in the Chewing and Swallowing (IV) domain. Mucosites on lips, tongue, floor of the mouth and the oropharynx were the most commonly found oral lesions after the remission induction phase. According to the NOT-S, there was an association between the occurrence of oral lesions in the evaluated patients and the presence of orofacial dysfunction (95% CI, p-value = 0.027). Conclusion It is suggested that orofacial dysfunction is frequent in the remission induction phase in children and adolescents with acute leukemia. Studies regarding these orofacial dysfunctions in this population, as well as their relationship with oral lesions, are needed in order to fully understand their functional impact.

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          STROBE initiative: guidelines on reporting observational studies.

          Reporting of observational studies is often inadequate, hampering the assessment of their strengths and weaknesses and, consequently, the generalization of study results. The initiative named Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) developed a checklist of 22 items, the STROBE Statement, with recommendations about what should be included in a more accurate and complete description of observational studies. Between June and December 2008, a group of Brazilian researchers was dedicated to the translation and adaptation of the STROBE Statement into Portuguese. The present study aimed to show the translation into Portuguese, introduce the discussion on the context of use, the potential and limitations of the STROBE initiative.
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                Author and article information

                Journal
                acr
                Audiology - Communication Research
                Audiol., Commun. Res.
                Academia Brasileira de Audiologia (São Paulo, SP, Brazil )
                2317-6431
                2022
                : 27
                : e2573
                Affiliations
                [04] São Paulo orgnameUniversidade Federal de São Paulo orgdiv1Programa de Pós-graduação em Distúrbios da Comunicação Humana Brazil
                [05] Manaus orgnameFundação Hospitalar de Hematologia e Hemoterapia do Amazonas orgdiv1Departamento de Odontologia Brazil
                [03] São Paulo São Paulo orgnameFaculdade de Ciências Médicas da Santa Casa de São Paulo orgdiv1Programa de Pós-graduação em Saúdes da Comunicação Humana Brazil
                [06] Manaus Amazonas orgnameUniversidade Federal do Amazonas orgdiv1Departamento de Patologia e Medicina Legal Brazil
                [01] Manaus Amazonas orgnameUniversidade do Estado do Amazonas orgdiv1Programa de Pós-graduação em Ciências Aplicadas à Hematologia Brazil
                [02] Manaus orgnameFundação Hospitalar de Hematologia e Hemoterapia do Amazonas orgdiv1Programa de Apoio a Iniciação Científica Brazil
                Article
                S2317-64312022000100314 S2317-6431(22)02700000314
                10.1590/2317-6431-2021-2573
                d000c178-2d6f-429b-b08b-3b1d55462cc7

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 13 September 2021
                : 30 March 2022
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 25, Pages: 0
                Product

                SciELO Brazil

                Categories
                Artigos Originais

                Disfagia,Acute leukemia,Orofacial dysfunction,Oral manifestations,Stomatognathic system,Dysphagia,Leucemia aguda,Disfunção orofacial,Manifestações orais,Sistema estomatognático

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