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      Adipose tissue in human infancy and childhood: An evolutionary perspective

      American Journal of Physical Anthropology
      Wiley

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          Positional cloning of the mouse obese gene and its human homologue.

          The mechanisms that balance food intake and energy expenditure determine who will be obese and who will be lean. One of the molecules that regulates energy balance in the mouse is the obese (ob) gene. Mutation of ob results in profound obesity and type II diabetes as part of a syndrome that resembles morbid obesity in humans. The ob gene product may function as part of a signalling pathway from adipose tissue that acts to regulate the size of the body fat depot.
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            The Expensive-Tissue Hypothesis: The Brain and the Digestive System in Human and Primate Evolution

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              The Evolution of Life Histories

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                Author and article information

                Journal
                American Journal of Physical Anthropology
                Am. J. Phys. Anthropol.
                Wiley
                00029483
                10968644
                1998
                1998
                : 107
                : S27
                : 177-209
                Article
                10.1002/(SICI)1096-8644(1998)107:27+<177::AID-AJPA7>3.0.CO;2-B
                c9a9817b-597d-47bf-a255-63cf58aefce8
                © 1998

                http://doi.wiley.com/10.1002/tdm_license_1.1

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