Patterns of Adherence to a Dapivirine Vaginal Ring for HIV-1 Prevention Among South African Women in a Phase III Randomized Controlled Trial.

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Abstract

Persistent use of HIV prevention methods can be a challenge, particularly for some younger women. The long-acting, discreet, woman-centric dapivirine vaginal ring offers promise as a prevention method with less user burden, which could support continued use. We assessed dapivirine vaginal ring use to understand adherence patterns and identify characteristics influencing patterns.

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Journal

Journal ID (iso-abbrev): J Acquir Immune Defic Syndr

Title: Journal of acquired immune deficiency syndromes (1999)

Publisher: Ovid Technologies (Wolters Kluwer Health)

ISSN (Electronic): 1944-7884

ISSN (Print): 1525-4135

Publication date (Electronic): Aug 01 2022

Volume: 90

Issue: 4

Affiliations

[1 ] Women's Global Health Imperative, RTI International, Berkeley, CA.

[2 ] Fred Hutchinson Cancer Research Center, Seattle, WA.

[3 ] Department of Biostatistics, University of Washington, Seattle, WA.

[4 ] Wits Reproductive Health and HIV Institute (Wits RHI), University of the Witwatersrand, Faculty of Health, Sciences, Johannesburg, South Africa.

[5 ] Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA; and.

[6 ] South African Medical Research Council, HPRU, Durban, South Africa.

[7 ] CAPRISA, Durban, South Africa.

[8 ] University of Pittsburgh, and Magee-Women's Research Institute, Pittsburgh, PA.

[9 ] FHI 360, Durham, NC.

[10 ] Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.

[11 ] Department of Global Health, Medicine, and Epidemiology, University of Washington, Seattle, WA.

[12 ] Current, Gilead Sciences, Foster City, CA.

[13 ] Center for AIDS Prevention Studies, Department of Medicine, University of California, San Francisco, CA.

[14 ] ASTRA consulting, Kensington, CA.

Article

Mid ID: NIHMS1792718 Publisher Item ID: 00126334-202208010-00008

DOI: 10.1097/QAI.0000000000002990

PMC ID: 9342948

PubMed ID: 35344520

SO-VID: c7034544-4ce6-4ddc-9d2d-5fb20fd2d8cb

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