Association of Respiratory Allergy, Asthma and Expression of the SARS-CoV-2 Receptor,  ACE2

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Abstract

Underlying respiratory allergy and experimental allergen exposure reduce the expression of the SARS-CoV-2 receptor, ACE2, which could lead to reduced COVID-19 susceptibility.

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Author and article information

Contributors

Daniel J. Jackson

Journal

Journal ID (nlm-ta): J Allergy Clin Immunol

Journal ID (iso-abbrev): J. Allergy Clin. Immunol

Title: The Journal of Allergy and Clinical Immunology

Publisher: Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology.

ISSN (Print): 0091-6749

ISSN (Electronic): 1097-6825

Publication date PMC-release: 22 April 2020

Publication date (Electronic): 22 April 2020

Affiliations

[1 ]University of Wisconsin School of Medicine and Public Health

[2 ]Washington University School of Medicine

[3 ]Columbia University College of Physicians and Surgeons

[4 ]Boston University School of Medicine

[5 ]Johns Hopkins University School of Medicine

[6 ]Rho, Inc

[7 ]MRC and Asthma UK, Centre in Allergic Mechanisms of Asthma

[8 ]The Immune Tolerance Network

[9 ]University of Chicago

[10 ]The National Institute of Allergy and Infectious Disease

[11 ]Department of Medicine, University of Washington

[12 ]Benaroya Research Institute, Systems Immunology Division

Author notes

[∗ ]Corresponding Author: Daniel J. Jackson, MD Associate Professor of Pediatrics and Medicine University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, CSC K4/936, Phone: 608-263-7686, Fax: 608-265-2207 djj@ 123456medicine.wisc.edu

Article

Publisher ID: S0091-6749(20)30551-0

DOI: 10.1016/j.jaci.2020.04.009

PMC ID: 7175851

PubMed ID: 32333915

SO-VID: c3ed4593-1f55-429b-a0a6-efb86c370434

License:

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

History

Date received : 7 April 2020

Date revision received : 15 April 2020

Date accepted : 16 April 2020

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Association of Respiratory Allergy, Asthma and Expression of the SARS-CoV-2 Receptor, ACE2

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