Left Atrial Appendage Occlusion : Current Advances and Remaining Challenges

Abstract

The field of left atrial appendage occlusion is rapidly evolving. However, several issues remain including the limited randomized efficacy data, peri-device leak, device-related thrombus, and the ongoing refinement of procedural techniques. In this article, we provide a contemporary overview of left atrial appendage occlusion focusing on 4 key remaining challenges: efficacy data, peri-device leak, device-related thrombus, and procedural optimization.

Central Illustration

Highlights

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  LAAO has emerged as a promising alternative to oral anticoagulation in selected patients with nonvalvular atrial fibrillation. Although remarkable progress in the field has been made, several questions remain open.

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  This study summarized the remaining issues with LAAO including the need for more randomized data, device-related thrombus, peri-device leak, and procedural optimization.

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  Ongoing randomized trials, newer devices, an improved planning software program, and procedural techniques will help address the remaining issues in the field.