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      Medical Cannabis Patients Under the Age of 21 in the United States: Description of Demographics and Conditions from a Large Patient Database, 2019-2023

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          Abstract

          Introduction

          Existing research on medical cannabis patients has often overlooked those younger than 21. This study aimed to detail the frequency and rate of pediatric medical cannabis patients in the US using a large patient database.

          Methods

          Utilizing Leafwell Patient Database data from 2019 to mid-2023, we described demographics and qualifying conditions, employing descriptive statistics and χ2 tests to discern differences between minors (0–17 years) and young adults (18–20 years). We calculated rates per 100,000 population by state.

          Results

          Analyzing 13,855 patients, 5.7% were minors and 94.3% were young adults. Anxiety emerged as the primary self-reported condition for both groups, yet differences were seen for other conditions. Differences were observed by race/ethnicity, health insurance status, residency in adult-use states, and number of reported conditions. Notably, both groups reported a similar average number of conditions.

          Conclusion

          This study underscores demographic distinctions between minor-aged medical cannabis patients and young adults. There is a need for comprehensive clinical research addressing efficacy, safety, and tailored guidelines specific for pediatric medical cannabis patients. Such insights are pivotal for healthcare providers and policymakers in navigating medical cannabis treatment protocols.

          Plain Language Summary

          This paper describes the demographics and medical conditions of medical cannabis patients under the age of 21 in the United States based on data from the Leafwell Patient Database spanning 2019 to mid-2023. We found that there is a significant number of medical cannabis users aged 20 or younger, with variations in demographics and conditions between minors (under 18) and young adults (18-20). The findings indicate that minor patients are predominantly white, non-Hispanic, residing in non-adult-use states, and report a lower number of conditions per patient compared to young adults. Anxiety, chronic pain, and PTSD are among the most commonly self-reported conditions for both age groups. There is need for additional clinical studies to understand the role of medical cannabis in addressing symptoms and improving the quality of life for conditions such as chronic pain, anxiety, and PTSD in the pediatric population. The study is limited by its reliance on self-reported data but represents the largest cohort of pediatric medical cannabis users in the world. Further investigation by academics and clinical scientists ought to inform the appropriate integration of medical cannabis in young patients.

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          Most cited references26

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          Clinical trials in children.

          Safety and efficacy data on many medicines used in children are surprisingly scarce. As a result children are sometimes given ineffective medicines or medicines with unknown harmful side effects. Better and more relevant clinical trials in children are needed to increase our knowledge of the effects of medicines and to prevent the delayed or non-use of beneficial therapies. Clinical trials provide reliable evidence of treatment effects by rigorous controlled testing of interventions on human subjects. Paediatric trials are more challenging to conduct than trials in adults because of the paucity of funding, uniqueness of children and particular ethical concerns. Although current regulations and initiatives are improving the scope, quantity and quality of trials in children, there are still deficiencies that need to be addressed to accelerate radically equitable access to evidence-based therapies in children.
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            The Health Effects of Cannabis and Cannabinoids : The Current State of Evidence and Recommendations for Research

            (2017)
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              Qualifying Conditions Of Medical Cannabis License Holders In The United States

              The evidence for cannabis’s treatment efficacy across different conditions varies widely, and comprehensive data on the conditions for which people use cannabis is lacking. We analyzed state registry data to provide nationwide estimates characterizing the qualifying conditions for which patients are licensed to use cannabis medically. We also compared the prevalence of medical cannabis qualifying conditions to recent evidence from the National Academies of Sciences, Engineering, and Medicine report on cannabis’s efficacy in treating each condition. Twenty states and Washington DC had available registry data on patient number, and fourteen states had data on patient-reported qualifying conditions. Chronic pain is currently and historically the most common qualifying condition reported by medical cannabis patients (67.5% in 2016). 85.5% of patient-reported qualifying conditions had either substantial or conclusive evidence of therapeutic efficacy. As medical cannabis use continues to increase, creating a nationwide patient registry will facilitate better understanding of use trends and potential effectiveness.
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                Author and article information

                Journal
                Adolesc Health Med Ther
                Adolesc Health Med Ther
                ahmt
                Adolescent Health, Medicine and Therapeutics
                Dove
                1179-318X
                23 July 2024
                2024
                : 15
                : 63-72
                Affiliations
                [1 ]Health Economics and Outcomes Research, Leafwell , Miami, FL, USA
                [2 ]Department of Health Sciences, DePaul University , Chicago, IL, USA
                Author notes
                Correspondence: Mitchell L Doucette, Health Economics and Outcomes Research , Leafwell Inc., Miami, FL, USA, Tel +1 203 293 9416, Email mdoucette@leafwell.com
                [†]

                Professor Douglas Bruce passed away on June 11th, 2024

                Author information
                http://orcid.org/0000-0002-5558-2218
                Article
                460560
                10.2147/AHMT.S460560
                11284137
                39076412
                b6c0e657-a5e3-4543-8820-928f761d6e1f
                © 2024 Doucette et al.

                This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License ( http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms ( https://www.dovepress.com/terms.php).

                History
                : 27 February 2024
                : 19 June 2024
                Page count
                Figures: 2, Tables: 2, References: 27, Pages: 10
                Funding
                Funded by: funding;
                This study was executed without external funding.
                Categories
                Original Research

                medical cannabis,pediatric,patient database,united states

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