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Association between early-onset Parkinson's disease and mutations in the parkin gene.
C B Lücking
1 ,
A Dürr ,
V Bonifati ,
J Vaughan ,
G De Michele ,
T Gasser ,
B S Harhangi ,
G Meco ,
P Denèfle ,
N W Wood ,
Y Agid ,
A Brice
May 25 2000
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Abstract
Mutations in the parkin gene have recently been identified in patients with early-onset Parkinson's disease, but the frequency of the mutations and the associated phenotype have not been assessed in a large series of patients.