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      Impaired interhemispheric synchrony in Parkinson's disease patients with apathy.

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          Abstract

          Apathy is a common non-motor symptom in Parkinson's disease (PD), yet the neural mechanism remains unknown. It has been reported that the lateralization of dopamine levels is correlated with apathetic symptoms. We aimed to ascertain the role of lateralization in the neuropathogenesis of apathy in PD.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): J Affect Disord
          Title: Journal of affective disorders
          Publisher: Elsevier BV
          ISSN (Electronic): 1573-2517
          ISSN (Print): 0165-0327
          Publication date (Electronic): Dec 01 2022
          Volume: 318
          Affiliations
          [1 ] Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
          [2 ] Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. Electronic address: da_sheng@126.com.
          [3 ] Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. Electronic address: kezhong_zhang1969@126.com.
          Article
          Publisher Item ID: S0165-0327(22)01001-1
          DOI: 10.1016/j.jad.2022.09.006
          PubMed ID: 36096372
          SO-VID: a8da49a7-271c-48a5-8f73-b406a4f18761
          History

          Keywords: Voxel-mirrored homotopic connectivity,Apathy,Asymmetry voxel-based morphometry analysis,Nucleus accumbens,Parkinson's disease,Putamen
          Data availability:
          Keywords: Voxel-mirrored homotopic connectivity, Apathy, Asymmetry voxel-based morphometry analysis, Nucleus accumbens, Parkinson's disease, Putamen

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