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      Delayed respiratory syncytial virus epidemic in children after relaxation of COVID-19 physical distancing measures, Ashdod, Israel, 2021

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          Abstract

          Following low incidence of respiratory syncytial virus (RSV) infections in 2020 during the COVID-19 pandemic, we noted a resurgence in hospitalised children in spring/summer 2021 following relaxation of public health measures. We compared this outbreak to previous autumn/winter seasons. We found higher weekly case numbers and incidence rates, more cases from urban neighbourhoods with lower socioeconomic status, and similar clinical presentation and severity. Public health implications include the re-evaluation of palivizumab administration and the need for surge capacity planning.

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          The impact of COVID-19 public health measures on detections of influenza and respiratory syncytial virus in children during the 2020 Australian winter

          Abstract Public health measures during the COVID-19 pandemic have potential to impact transmission of other respiratory viruses. We found 98.0% and 99.4% reductions in RSV and influenza detections respectively in Western Australian children through winter 2020; despite reopening of schools. Border closures have likely been important in limiting introductions from abroad.
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            Latitudinal Variations in Seasonal Activity of Influenza and Respiratory Syncytial Virus (RSV): A Global Comparative Review

            Background There is limited information on influenza and respiratory syncytial virus (RSV) seasonal patterns in tropical areas, although there is renewed interest in understanding the seasonal drivers of respiratory viruses. Methods We review geographic variations in seasonality of laboratory-confirmed influenza and RSV epidemics in 137 global locations based on literature review and electronic sources. We assessed peak timing and epidemic duration and explored their association with geography and study settings. We fitted time series model to weekly national data available from the WHO influenza surveillance system (FluNet) to further characterize seasonal parameters. Results Influenza and RSV activity consistently peaked during winter months in temperate locales, while there was greater diversity in the tropics. Several temperate locations experienced semi-annual influenza activity with peaks occurring in winter and summer. Semi-annual activity was relatively common in tropical areas of Southeast Asia for both viruses. Biennial cycles of RSV activity were identified in Northern Europe. Both viruses exhibited weak latitudinal gradients in the timing of epidemics by hemisphere, with peak timing occurring later in the calendar year with increasing latitude (P<0.03). Time series model applied to influenza data from 85 countries confirmed the presence of latitudinal gradients in timing, duration, seasonal amplitude, and between-year variability of epidemics. Overall, 80% of tropical locations experienced distinct RSV seasons lasting 6 months or less, while the percentage was 50% for influenza. Conclusion Our review combining literature and electronic data sources suggests that a large fraction of tropical locations experience focused seasons of respiratory virus activity in individual years. Information on seasonal patterns remains limited in large undersampled regions, included Africa and Central America. Future studies should attempt to link the observed latitudinal gradients in seasonality of viral epidemics with climatic and population factors, and explore regional differences in disease transmission dynamics and attack rates.
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              COVID-19 dynamics after a national immunization program in Israel

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                Author and article information

                Journal
                Euro Surveill
                Euro Surveill
                eurosurveillance
                Eurosurveillance
                European Centre for Disease Prevention and Control (ECDC)
                1025-496X
                1560-7917
                22 July 2021
                : 26
                : 29
                : 2100706
                Affiliations
                [1 ]Department of Pediatrics, Samson Assuta Ashdod University Hospital, Ashdod, Israel
                [2 ]Faculty of Health Sciences, Ben-Gurion University in the Negev, Beer-Sheva, Israel
                [3 ]Israel Center for Disease Control, Ministry of Health, Tel Hashomer, Ramat Gan, Israel
                [4 ]Department of Epidemiology and Preventive Medicine, School for Public Health, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
                [5 ]Microbiology laboratory, Samson Assuta Ashdod University Hospital, Ashdod, Israel
                [6 ]Infectious Diseases Unit, Samson Assuta Ashdod University Hospital, Ashdod, Israel
                Author notes

                Correspondence: Moran Weinberger Opek ( moranw@ 123456assuta.co.il )

                Article
                2100706 2100706
                10.2807/1560-7917.ES.2021.26.29.2100706
                8299746
                34296678
                a49b7eae-f630-4e7f-855a-9e2e01eeae2d
                This article is copyright of the authors or their affiliated institutions, 2021.

                This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.

                History
                : 14 July 2021
                : 22 July 2021
                Categories
                Rapid Communication
                Custom metadata
                293

                respiratory syncytial virus (rsv),seasonality,summer,covid-19,physical distancing,palivizumab administration

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