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      Genetic Influences on Educational Achievement in Cross-National Perspective

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          Abstract

          There is a growing interest in how social conditions moderate genetic influences on education [gene–environment interactions (GxE)]. Previous research has focused on the family, specifically parents’ social background, and has neglected the institutional environment. To assess the impact of macro-level influences, we compare genetic influences on educational achievement and their social stratification across Germany, Norway, Sweden, and the United States. We combine well-established GxE-conceptualizations with the comparative stratification literature and propose that educational systems and welfare-state regimes affect the realization of genetic potential. We analyse population-representative survey data on twins (Germany and the United States) and twin registers (Norway and Sweden), and estimate genetically sensitive variance decomposition models. Our comparative design yields three main findings. First, Germany stands out with comparatively weak genetic influences on educational achievement suggesting that early tracking limits the realization thereof. Second, in the United States genetic influences are comparatively strong and similar in size compared to the Nordic countries. Third, in Sweden genetic influences are stronger among disadvantaged families supporting the expectation that challenging and uncertain circumstances promote genetic expression. This ideosyncratic finding must be related to features of Swedish social institutions or welfare-state arrangements that are not found in otherwise similar countries.

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          Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

          Here we conducted a large-scale genetic association analysis of educational attainment in a sample of approximately 1.1 million individuals and identify 1,271 independent genome-wide-significant SNPs. For the SNPs taken together, we found evidence of heterogeneous effects across environments. The SNPs implicate genes involved in brain-development processes and neuron-to-neuron communication. In a separate analysis of the X chromosome, we identify 10 independent genome-wide-significant SNPs and estimate a SNP heritability of around 0.3% in both men and women, consistent with partial dosage compensation. A joint (multi-phenotype) analysis of educational attainment and three related cognitive phenotypes generates polygenic scores that explain 11-13% of the variance in educational attainment and 7-10% of the variance in cognitive performance. This prediction accuracy substantially increases the utility of polygenic scores as tools in research.
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            Socioeconomic Status Modifies Heritability of IQ in Young Children

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              Social Foundations of Postindustrial Economies

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                Author and article information

                Contributors
                (View ORCID Profile)
                Journal
                European Sociological Review
                Oxford University Press (OUP)
                0266-7215
                1468-2672
                February 23 2022
                February 23 2022
                Affiliations
                [1 ]Department of Sociology and Human Geography, University of Oslo, 0317 Oslo, Norway
                [2 ]Department of Sociology, University of Tübingen, 72074 Tübingen, Germany
                [3 ]Institut des Sciences Sociales, University of Lausanne, 1015 Lausanne, Switzerland
                [4 ]Swedish Institute for Social Research (SOFI), Stockholm University, 10691 Stockholm, Sweden
                [5 ]Max Planck Institute for Demographic Research, 18057 Rostock; Department of Sociology, Stockholm University, 10691 Stockholm; Swedish Collegium for Advanced Study, 75238 Uppsala, Sweden
                [6 ]Department of Sociology, Princeton University, Princeton, NJ 08544, USA; National Bureau for Economic Research, Cambridge, MA 02138, USA
                [7 ]Political Science Department, New York University, New York, NY 10012, USA
                [8 ]Institute of Behavioral Science and Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80303, USA
                Article
                10.1093/esr/jcac014
                9b3687b2-7ff8-4454-98ca-45b235068c81
                © 2022

                https://creativecommons.org/licenses/by-nc/4.0/

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