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      Non‐invasive home telemonitoring in patients with decompensated heart failure: a systematic review and meta‐analysis

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          Abstract

          We planned this systematic review and meta‐analysis to study an estimate of the effect of non‐invasive home telemonitoring (TM) in the treatment of patients with recently decompensated heart failure (HF). A systematic literature search was conducted in the Medline, Cinahl, and Scopus databases to look for randomized controlled studies comparing TM with standard care in the treatment of patients with recently decompensated HF. The main outcomes of interest were all‐cause hospitalizations and mortality. Eleven original articles met our eligibility criteria. The pooled estimate of the relative risk of all‐cause hospitalization in the TM group compared with standard care was 0.95 (95% CI 0.84–1.08, P = 0.43) and the relative risk of all‐cause death was 0.83 (95% CI 0.63–1.09, P = 0.17). There was significant clinical heterogeneity among primary studies. HF medication could be directly altered in three study interventions, and two of these had a statistically significant effect on all‐cause hospitalizations. The pooled effect estimate of TM interventions on all‐cause hospitalizations and all‐cause death in patients with recently decompensated heart failure was neutral.

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          Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.

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            Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction

            In patients with type 2 diabetes, inhibitors of sodium-glucose cotransporter 2 (SGLT2) reduce the risk of a first hospitalization for heart failure, possibly through glucose-independent mechanisms. More data are needed regarding the effects of SGLT2 inhibitors in patients with established heart failure and a reduced ejection fraction, regardless of the presence or absence of type 2 diabetes.
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              Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure

              Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure in patients regardless of the presence or absence of diabetes. More evidence is needed regarding the effects of these drugs in patients across the broad spectrum of heart failure, including those with a markedly reduced ejection fraction.
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                Author and article information

                Contributors
                teemu.drews@gmail.com
                Journal
                ESC Heart Fail
                ESC Heart Fail
                10.1002/(ISSN)2055-5822
                EHF2
                ESC Heart Failure
                John Wiley and Sons Inc. (Hoboken )
                2055-5822
                24 June 2021
                October 2021
                : 8
                : 5 ( doiID: 10.1002/ehf2.v8.5 )
                : 3696-3708
                Affiliations
                [ 1 ] Department of Cardiology South Karelia Central Hospital Lappeenranta Finland
                [ 2 ] Heart and Lung Center Helsinki University Central Hospital Helsinki Finland
                [ 3 ] Department of Medicine Central Finland Health Care District Jyväskylä Finland
                [ 4 ] Institute of Clinical Medicine, Department of Medicine University of Eastern Finland Kuopio Finland
                [ 5 ] Päijät‐Häme Joint Authority for Health and Well‐being Lahti Finland
                Author notes
                [*] [* ]Correspondence to: Teemu Drews, Heart and Lung Center, Helsinki University Central Hospital, Helsinki, Finland. Tel: +358‐40‐5648295. Email: teemu.drews@ 123456gmail.com
                Article
                EHF213475 ESCHF-21-00267
                10.1002/ehf2.13475
                8497386
                34165912
                9abc79cb-d96f-407c-95c1-37514bfb36dd
                © 2021 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

                History
                : 16 May 2021
                : 11 March 2021
                : 01 June 2021
                Page count
                Figures: 2, Tables: 4, Pages: 13, Words: 3235
                Categories
                Review
                Reviews
                Custom metadata
                2.0
                October 2021
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.0.8 mode:remove_FC converted:07.10.2021

                heart failure,telemedicine,telemonitoring,telerehabilitation,remote consultation,mortality,hospitalization,quality of life

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