[1
]From Genzyme Corp (K.A.V., Y.L., C.J., M.A.G., G.Y.A., R.J.G.) Framingham, Mass.;
Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School (M.A.G.);
and Department of Medicine and Biomedical Research, St Elizabeth’s Medical Center,
Tufts Medical School (K.-G.S., M.M., R.A.T., J.M.I.), Boston, Mass. The first 2 authors
contributed equally to this work.