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      Development of a Credible Virtual Clinician Promoting Colorectal Cancer Screening via Telehealth Apps for and by Black Men: Qualitative Study

      research-article
      , BSc, MA, PhD 1 , 2 , , , BA, MPH, CPH, PhD 2 , , PhD 3 , 4 , , BA, PhD 2 , 5 , , PhD 2 , , BS 1 , , BA, PhD 6 , , BA 6 , , BSc, PhD 6 , , PhD 7 , , PhD 8 , , MD, MSc, CAQSM, FAAFP, DABF 9 , , MD, FACP 10 , 11 , , BSc, PhD 2 , 5
      (Reviewer)
      JMIR Formative Research
      JMIR Publications
      telehealth, digital health, eHealth, colorectal cancer, Black men, virtual human, technology, cancer screening, app, cancer, prevention, development

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          Abstract

          Background

          Traditionally, promotion of colorectal cancer (CRC) screening among Black men was delivered by community health workers, patient navigators, and decision aids (printed text or video media) at clinics and in the community setting. A novel approach to increase CRC screening of Black men includes developing and utilizing a patient-centered, tailored message delivered via virtual human technology in the privacy of one’s home.

          Objective

          The objective of this study was to incorporate the perceptions of Black men in the development of a virtual clinician (VC) designed to deliver precision messages promoting the fecal immunochemical test (FIT) kit for CRC screening among Black men in a future clinical trial.

          Methods

          Focus groups of Black men were recruited to understand their perceptions of a Black male VC. Specifically, these men identified source characteristics that would enhance the credibility of the VC. The modality, agency, interactivity, and navigability (MAIN) model, which examines how interface features affect the user’s psychology through four affordances (modality, agency, interactivity, and navigability), was used to assess the presumed credibility of the VC and likability of the app from the focus group transcripts. Each affordance triggers heuristic cues that stimulate a positive or a negative perception of trustworthiness, believability, and understandability, thereby increasing source credibility.

          Results

          In total, 25 Black men were recruited from the community and contributed to the development of 3 iterations of a Black male VC over an 18-month time span. Feedback from the men enhanced the visual appearance of the VC, including its movement, clothing, facial expressions, and environmental surroundings. Heuristics, including social presence, novelty, and authority, were all recognized by the final version of the VC, and creditably was established. The VC was named Agent Leveraging Empathy for eXams (ALEX) and referred to as “brother-doctor,” and participants stated “wanting to interact with ALEX over their regular doctor.”

          Conclusions

          Involving Black men in the development of a digital health care intervention is critical. This population is burdened by cancer health disparities, and incorporating their perceptions in telehealth interventions will create awareness of the need to develop targeted messages for Black men.

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          Most cited references35

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          Global Cancer Statistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

          This article provides a status report on the global burden of cancer worldwide using the GLOBOCAN 2018 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer, with a focus on geographic variability across 20 world regions. There will be an estimated 18.1 million new cancer cases (17.0 million excluding nonmelanoma skin cancer) and 9.6 million cancer deaths (9.5 million excluding nonmelanoma skin cancer) in 2018. In both sexes combined, lung cancer is the most commonly diagnosed cancer (11.6% of the total cases) and the leading cause of cancer death (18.4% of the total cancer deaths), closely followed by female breast cancer (11.6%), prostate cancer (7.1%), and colorectal cancer (6.1%) for incidence and colorectal cancer (9.2%), stomach cancer (8.2%), and liver cancer (8.2%) for mortality. Lung cancer is the most frequent cancer and the leading cause of cancer death among males, followed by prostate and colorectal cancer (for incidence) and liver and stomach cancer (for mortality). Among females, breast cancer is the most commonly diagnosed cancer and the leading cause of cancer death, followed by colorectal and lung cancer (for incidence), and vice versa (for mortality); cervical cancer ranks fourth for both incidence and mortality. The most frequently diagnosed cancer and the leading cause of cancer death, however, substantially vary across countries and within each country depending on the degree of economic development and associated social and life style factors. It is noteworthy that high-quality cancer registry data, the basis for planning and implementing evidence-based cancer control programs, are not available in most low- and middle-income countries. The Global Initiative for Cancer Registry Development is an international partnership that supports better estimation, as well as the collection and use of local data, to prioritize and evaluate national cancer control efforts. CA: A Cancer Journal for Clinicians 2018;0:1-31. © 2018 American Cancer Society.
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            Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods

            Estimates of the worldwide incidence and mortality from 36 cancers and for all cancers combined for the year 2018 are now available in the GLOBOCAN 2018 database, compiled and disseminated by the International Agency for Research on Cancer (IARC). This paper reviews the sources and methods used in compiling the cancer statistics in 185 countries. The validity of the national estimates depends upon the representativeness of the source information, and to take into account possible sources of bias, uncertainty intervals are now provided for the estimated sex- and site-specific all-ages number of new cancer cases and cancer deaths. We briefly describe the key results globally and by world region. There were an estimated 18.1 million (95% UI: 17.5-18.7 million) new cases of cancer (17 million excluding non-melanoma skin cancer) and 9.6 million (95% UI: 9.3-9.8 million) deaths from cancer (9.5 million excluding non-melanoma skin cancer) worldwide in 2018.
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              Understanding factors affecting patient and public engagement and recruitment to digital health interventions: a systematic review of qualitative studies

              Background Numerous types of digital health interventions (DHIs) are available to patients and the public but many factors affect their ability to engage and enrol in them. This systematic review aims to identify and synthesise the qualitative literature on barriers and facilitators to engagement and recruitment to DHIs to inform future implementation efforts. Methods PubMed, MEDLINE, CINAHL, Embase, Scopus and the ACM Digital Library were searched for English language qualitative studies from 2000 – 2015 that discussed factors affecting engagement and enrolment in a range of DHIs (e.g. ‘telemedicine’, ‘mobile applications’, ‘personal health record’, ‘social networking’). Text mining and additional search strategies were used to identify 1,448 records. Two reviewers independently carried out paper screening, quality assessment, data extraction and analysis. Data was analysed using framework synthesis, informed by Normalization Process Theory, and Burden of Treatment Theory helped conceptualise the interpretation of results. Results Nineteen publications were included in the review. Four overarching themes that affect patient and public engagement and enrolment in DHIs emerged; 1) personal agency and motivation; 2) personal life and values; 3) the engagement and recruitment approach; and 4) the quality of the DHI. The review also summarises engagement and recruitment strategies used. A preliminary DIgital Health EnGagement MOdel (DIEGO) was developed to highlight the key processes involved. Existing knowledge gaps are identified and a number of recommendations made for future research. Study limitations include English language publications and exclusion of grey literature. Conclusion This review summarises and highlights the complexity of digital health engagement and recruitment processes and outlines issues that need to be addressed before patients and the public commit to digital health and it can be implemented effectively. More work is needed to create successful engagement strategies and better quality digital solutions that are personalised where possible and to gain clinical accreditation and endorsement when appropriate. More investment is also needed to improve computer literacy and ensure technologies are accessible and affordable for those who wish to sign up to them. Systematic review registration International Prospective Register of Systematic Reviews CRD42015029846 Electronic supplementary material The online version of this article (doi:10.1186/s12911-016-0359-3) contains supplementary material, which is available to authorized users.
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                Author and article information

                Contributors
                Journal
                JMIR Form Res
                JMIR Form Res
                JFR
                JMIR Formative Research
                JMIR Publications (Toronto, Canada )
                2561-326X
                December 2021
                24 December 2021
                : 5
                : 12
                : e28709
                Affiliations
                [1 ] Department of Natural Sciences Bethune Cookman University Daytona, FL United States
                [2 ] STEM Translational Communication Center College of Journalism University of Florida Gainesville, FL United States
                [3 ] Harvard Medical School Harvard University Boston, MA United States
                [4 ] Mongan Institute’s Health Policy Research Center Massachusetts General Hospital Boston, MA United States
                [5 ] UF Health Cancer Center University of Florida Gainesville, FL United States
                [6 ] Computer and Information Science and Engineering University of Florida Gainesville, FL United States
                [7 ] Center for Health Equity & Community Engagement Research Mayo Clinic Jacksonville, FL United States
                [8 ] Department of Health Outcomes and Biomedical Informatics College of Medicine University of Florida Gainesville, FL United States
                [9 ] Family Medicine Medical University of South Carolina Charleston, SC United States
                [10 ] Gastrointestinal (GI) Oncology Center University of Florida Gainesville, FL United States
                [11 ] UF Health Medical Oncology – Davis Cancer University of Florida Gainesville, FL United States
                Author notes
                Corresponding Author: Danyell Wilson-Howard wilsonda@ 123456cookman.edu
                Author information
                https://orcid.org/0000-0002-5912-4097
                https://orcid.org/0000-0003-3975-0274
                https://orcid.org/0000-0001-5769-4961
                https://orcid.org/0000-0003-2310-1237
                https://orcid.org/0000-0002-3041-9561
                https://orcid.org/0000-0002-5877-4143
                https://orcid.org/0000-0002-3769-7679
                https://orcid.org/0000-0002-6799-6784
                https://orcid.org/0000-0002-1190-3729
                https://orcid.org/0000-0003-3796-1385
                https://orcid.org/0000-0003-4366-0757
                https://orcid.org/0000-0003-3937-1733
                https://orcid.org/0000-0002-6249-9180
                https://orcid.org/0000-0001-9950-9170
                Article
                v5i12e28709
                10.2196/28709
                8751682
                34780346
                8bd7e88b-da49-48ce-a04c-3557d33e66cc
                ©Danyell Wilson-Howard, Melissa J Vilaro, Jordan M Neil, Eric J Cooks, Lauren N Griffin, Taylor T Ashley, Fatemeh Tavassoli, Mohan S Zalake, Benjamin C Lok, Folakemi T Odedina, Francois Modave, Peter J Carek, Thomas J George, Janice L Krieger. Originally published in JMIR Formative Research (https://formative.jmir.org), 24.12.2021.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Formative Research, is properly cited. The complete bibliographic information, a link to the original publication on https://formative.jmir.org, as well as this copyright and license information must be included.

                History
                : 16 March 2021
                : 7 April 2021
                : 21 April 2021
                : 6 October 2021
                Categories
                Original Paper
                Original Paper

                telehealth,digital health,ehealth,colorectal cancer,black men,virtual human,technology,cancer screening,app,cancer,prevention,development

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