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      Significant impacts of COVID-19 lockdown on urban air pollution in Kolkata (India) and amelioration of environmental health

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          Abstract

          The fatal novel coronavirus (COVID-19) pandemic disease smashes the normal tempo of global socio-economic and cultural livelihood. Most of the countries impose a lockdown system with social distancing measures to arrest the rapid transmission of this virus into the human body. The objective of this study is to examine the status of air quality during and pre-COVID-19 lockdown and to recommend some long-term sustainable environmental management plan. The pollution data like PM 10, PM 2.5, O 3, SO 2, NO 2 and CO have been obtained from State Pollution Control Board under Govt. of West Bengal. Similarly, various land surface temperature (LST) maps have been prepared using LANDSAT-8 OLI and LANDSAT-7 ETM + images of USGS. The maps of NO 2 and aerosol concentration over Indian subcontinent have been taken from ESA and NASA. The digital thematic maps and diagrams have been depicted by Grapher 13 and Arc GIS 10.3 platforms. The result shows that the pollutants like CO, NO 2 and SO 2 are significantly decreased, while the average level of O 3 has been slightly increased in 2020 during the lockdown due to close-down of all industrial and transport activities. Meanwhile, around 17.5% was the mean reduction of PM 10 and PM 2.5 during lockdown compared with previous years owing to complete stop of vehicles movement, burning of biomass and dust particles from the construction works. This study recommends some air pollution-tolerant plant species (in urban vacant spaces and roof tops) for long-term cohabitation among environment, society and development.

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          Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

          Summary Background A recent cluster of pneumonia cases in Wuhan, China, was caused by a novel betacoronavirus, the 2019 novel coronavirus (2019-nCoV). We report the epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of these patients. Methods All patients with suspected 2019-nCoV were admitted to a designated hospital in Wuhan. We prospectively collected and analysed data on patients with laboratory-confirmed 2019-nCoV infection by real-time RT-PCR and next-generation sequencing. Data were obtained with standardised data collection forms shared by WHO and the International Severe Acute Respiratory and Emerging Infection Consortium from electronic medical records. Researchers also directly communicated with patients or their families to ascertain epidemiological and symptom data. Outcomes were also compared between patients who had been admitted to the intensive care unit (ICU) and those who had not. Findings By Jan 2, 2020, 41 admitted hospital patients had been identified as having laboratory-confirmed 2019-nCoV infection. Most of the infected patients were men (30 [73%] of 41); less than half had underlying diseases (13 [32%]), including diabetes (eight [20%]), hypertension (six [15%]), and cardiovascular disease (six [15%]). Median age was 49·0 years (IQR 41·0–58·0). 27 (66%) of 41 patients had been exposed to Huanan seafood market. One family cluster was found. Common symptoms at onset of illness were fever (40 [98%] of 41 patients), cough (31 [76%]), and myalgia or fatigue (18 [44%]); less common symptoms were sputum production (11 [28%] of 39), headache (three [8%] of 38), haemoptysis (two [5%] of 39), and diarrhoea (one [3%] of 38). Dyspnoea developed in 22 (55%) of 40 patients (median time from illness onset to dyspnoea 8·0 days [IQR 5·0–13·0]). 26 (63%) of 41 patients had lymphopenia. All 41 patients had pneumonia with abnormal findings on chest CT. Complications included acute respiratory distress syndrome (12 [29%]), RNAaemia (six [15%]), acute cardiac injury (five [12%]) and secondary infection (four [10%]). 13 (32%) patients were admitted to an ICU and six (15%) died. Compared with non-ICU patients, ICU patients had higher plasma levels of IL2, IL7, IL10, GSCF, IP10, MCP1, MIP1A, and TNFα. Interpretation The 2019-nCoV infection caused clusters of severe respiratory illness similar to severe acute respiratory syndrome coronavirus and was associated with ICU admission and high mortality. Major gaps in our knowledge of the origin, epidemiology, duration of human transmission, and clinical spectrum of disease need fulfilment by future studies. Funding Ministry of Science and Technology, Chinese Academy of Medical Sciences, National Natural Science Foundation of China, and Beijing Municipal Science and Technology Commission.
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            Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

            Summary Background Since December, 2019, Wuhan, China, has experienced an outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Epidemiological and clinical characteristics of patients with COVID-19 have been reported but risk factors for mortality and a detailed clinical course of illness, including viral shedding, have not been well described. Methods In this retrospective, multicentre cohort study, we included all adult inpatients (≥18 years old) with laboratory-confirmed COVID-19 from Jinyintan Hospital and Wuhan Pulmonary Hospital (Wuhan, China) who had been discharged or had died by Jan 31, 2020. Demographic, clinical, treatment, and laboratory data, including serial samples for viral RNA detection, were extracted from electronic medical records and compared between survivors and non-survivors. We used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death. Findings 191 patients (135 from Jinyintan Hospital and 56 from Wuhan Pulmonary Hospital) were included in this study, of whom 137 were discharged and 54 died in hospital. 91 (48%) patients had a comorbidity, with hypertension being the most common (58 [30%] patients), followed by diabetes (36 [19%] patients) and coronary heart disease (15 [8%] patients). Multivariable regression showed increasing odds of in-hospital death associated with older age (odds ratio 1·10, 95% CI 1·03–1·17, per year increase; p=0·0043), higher Sequential Organ Failure Assessment (SOFA) score (5·65, 2·61–12·23; p<0·0001), and d-dimer greater than 1 μg/mL (18·42, 2·64–128·55; p=0·0033) on admission. Median duration of viral shedding was 20·0 days (IQR 17·0–24·0) in survivors, but SARS-CoV-2 was detectable until death in non-survivors. The longest observed duration of viral shedding in survivors was 37 days. Interpretation The potential risk factors of older age, high SOFA score, and d-dimer greater than 1 μg/mL could help clinicians to identify patients with poor prognosis at an early stage. Prolonged viral shedding provides the rationale for a strategy of isolation of infected patients and optimal antiviral interventions in the future. Funding Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences; National Science Grant for Distinguished Young Scholars; National Key Research and Development Program of China; The Beijing Science and Technology Project; and Major Projects of National Science and Technology on New Drug Creation and Development.
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              A Novel Coronavirus from Patients with Pneumonia in China, 2019

              Summary In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A previously unknown betacoronavirus was discovered through the use of unbiased sequencing in samples from patients with pneumonia. Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily. Different from both MERS-CoV and SARS-CoV, 2019-nCoV is the seventh member of the family of coronaviruses that infect humans. Enhanced surveillance and further investigation are ongoing. (Funded by the National Key Research and Development Program of China and the National Major Project for Control and Prevention of Infectious Disease in China.)
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                Author and article information

                Contributors
                biswajitbera007@gmail.com
                sumana.aarohi@gmail.com
                shitpravat2013@gmail.com
                nairitasengupta2@gmail.com
                soumiksaha577@gmail.com
                Journal
                Environ Dev Sustain
                Environ Dev Sustain
                Environment, Development and Sustainability
                Springer Netherlands (Dordrecht )
                1387-585X
                1573-2975
                28 July 2020
                : 1-28
                Affiliations
                [1 ]GRID grid.440737.3, Sidho-Kanho-Birsha University, ; P.O. Purulia, Ranchi Road, Purulia, West Bengal 723104 India
                [2 ]GRID grid.59056.3f, ISNI 0000 0001 0664 9773, Department of Geography, , University of Calcutta (Jogesh Chandra Chaudhuri College), ; 30, Prince Anwar Shah Road, Kolkata, 700 033 India
                [3 ]Department of Geography, Raja Narendralal Khan Women’s College, Gope Palace, P.O. Vidyasagar University, Paschim Medinipur, Phulpahari, West Bengal 721102 India
                [4 ]GRID grid.449077.9, Department of Geography, , Diamond Harbour Women’s University, ; Sarisha, West Bengal 743368 India
                [5 ]GRID grid.59056.3f, ISNI 0000 0001 0664 9773, Independent Researcher, Department of Geography, , University of Calcutta, ; Ballygunge, Kolkata, West Bengal 700019 India
                Author information
                http://orcid.org/0000-0002-0957-8023
                http://orcid.org/0000-0001-5834-0495
                http://orcid.org/0000-0002-4887-4191
                Article
                898
                10.1007/s10668-020-00898-5
                7384893
                32837282
                76f5619c-caf5-48ea-8162-6042eca52e9a
                © Springer Nature B.V. 2020

                This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

                History
                : 6 June 2020
                : 18 July 2020
                Categories
                Article

                covid-19,lockdown system,air quality,parameters,sustainable
                covid-19, lockdown system, air quality, parameters, sustainable

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