Cerebellar atrophy in neurodegeneration-a meta-analysis.

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Abstract

The cerebellum has strong cortical and subcortical connectivity, but is rarely taken into account for clinical diagnosis in many neurodegenerative conditions, particularly in the absence of clinical ataxia. The current meta-analysis aims to assess patterns of cerebellar grey matter atrophy in seven neurodegenerative conditions (Alzheimer's disease (AD), Parkinson's disease (PD) and Huntington's disease (HD), frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS), multiple system atrophy (MSA), progressive supranuclear palsy (MSP)).

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Journal

Journal ID (iso-abbrev): J. Neurol. Neurosurg. Psychiatr.

Title: Journal of neurology, neurosurgery, and psychiatry

Publisher: BMJ

ISSN (Electronic): 1468-330X

ISSN (Print): 0022-3050

Publication date (Electronic): May 13 2017

Affiliations

[1 ] Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands.

[2 ] Mental Health Program, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

[3 ] Behavioural and Clinical Neuroscience Institute and Department of Psychology, University of Cambridge, Cambridge, UK.

[4 ] Brain and Mind Centre, Sydney Medical School, The University of Sydney, Sydney, Australia.

[5 ] Neuroscience Research Australia, Sydney, Australia.

[6 ] Department of Clinical Neuroscience, University of Cambridge, Cambridge, UK.

[7 ] Norwich Medical School, University of East Anglia, Norwich, UK.

[8 ] Dementia and Complexity in Later Life, NHS Norfolk and Suffolk Foundation Trust, UK.

Article

Publisher Item ID: jnnp-2017-315607

DOI: 10.1136/jnnp-2017-315607

PubMed ID: 28501823

SO-VID: 76483536-e1f2-46e8-b4fd-817609d4b8c4

History

Keywords: DEMENTIA,META-ANALYSIS,MRI

Data availability:

Keywords: DEMENTIA, META-ANALYSIS, MRI

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