Surveillance of donated blood during the 2016 arbovirus outbreak in Brazil.

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Abstract

Reports of arboviral transmission via blood transfusion may be a cause of concern among asymptomatic infected donors. This study evaluated the presence of arboviruses in donated blood products during the 2016 outbreak in Vitória da Conquista (Bahia-Brazil). Serum samples (n = 676) were screened for ZIKV, CHIKV, and the four DENV serotypes using a one-step reverse transcriptase-based Real-Time Polymerase Chain Reaction (RT-PCR). No samples tested positive for any of the targets, whereas positive controls performed as expected. The results suggest a low risk of arboviral transmission via transfusion of blood products in the endemic area studied during the 2016 outbreak.

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Journal

Journal ID (iso-abbrev): J Med Virol

Title: Journal of medical virology

Publisher: Wiley

ISSN (Electronic): 1096-9071

ISSN (Print): 0146-6615

Publication date (Electronic): August 2018

Volume: 90

Issue: 8

Affiliations

[1 ] Instituto Gonçalo Moniz-IGM/FIOCRUZ, Salvador, BA, Brazil.

[2 ] IMS-Instituto Multidisciplinar em Saúde, UFBA, Vitória da Conquista, BA, Brazil.

[3 ] Serviço de Hemoterapia do Sudoeste, Vitória da Conquista, BA, Brazil.

[4 ] IBMP-Instituto de Biologia Molecular do Paraná, Curitiba, PR, Brazil.

[5 ] Instituto Carlos Chagas-ICC/FIOCRUZ, Curitiba, PR, Brazil.

[6 ] Instituto Nacional de Ciência e Tecnologia de Investigação em Imunologia, São Paulo, SP, Brazil.

Article

DOI: 10.1002/jmv.25193

PubMed ID: 29667206

SO-VID: 75bf1dc3-6c51-41e8-be2d-75ac329c1c51

History

Keywords: transfusion,NAT,ZIKV

Data availability:

Keywords: transfusion, NAT, ZIKV

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