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      Association analysis of ERCC5 gene polymorphisms with risk of breast cancer in Han women of northwest China.

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          Abstract

          ERCC5 plays an important role in DNA damage repair. Mutations in it will lead to DNA repair defects and genomic instability. Its functional single nucleotide polymorphisms (SNPs) may alter DNA repair capacity and affect cancer susceptibility.

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          Author and article information

          Journal
          Breast Cancer
          Breast cancer (Tokyo, Japan)
          Springer Nature
          1880-4233
          1340-6868
          May 2016
          : 23
          : 3
          Affiliations
          [1 ] Gansu Provincial Academy of Medical Sciences and Gansu Provincial Cancer Hospital, 2 Xiaoxihu East Street, Qilihe Region, Lanzhou, 730050, Gansu, People's Republic of China.
          [2 ] Gansu Provincial Academy of Medical Sciences and Gansu Provincial Cancer Hospital, 2 Xiaoxihu East Street, Qilihe Region, Lanzhou, 730050, Gansu, People's Republic of China. haxisu@sina.com.
          Article
          10.1007/s12282-015-0590-2
          10.1007/s12282-015-0590-2
          25644244
          759037d5-e837-44b2-8b86-2b903cb7b0c3
          History

          Breast cancer,ERCC5,Single nucleotide polymorphism
          Breast cancer, ERCC5, Single nucleotide polymorphism

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