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      Impfungen bei Kinderwunsch und Schwangerschaft Translated title: Vaccinations Before and During Pregnancy

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          Abstract

          Impfungen vor und während einer Schwangerschaft kommen eine wichtige Bedeutung zu – bei konsequenter Impfstrategie können Infektionen gänzlich verhindert werden bzw. der Krankheitsverlauf abgemildert werden und auch die Risiken für Komplikationen bei Mutter und Kind vermieden werden. Die Empfehlungen zu den Impfungen vor einer Schwangerschaft orientieren sich an den allgemeinen Impfempfehlungen. Während einer Schwangerschaft wird ausdrücklich zu zwei Impfungen geraten. Zum Einen ist dies die Impfung gegen saisonale Influenza, die die Schwangere vor der Infektion schützen soll, weil sie ein höheres Risiko für schwere Verläufe oder Komplikationen hat. Zum Anderen wird die Immunisierung gegen Pertussis empfohlen, die dem Neugeborenen während der ersten Lebensmonate Schutz bietet. Während der Stillzeit sollte ein unzureichender Impfschutz gemäß den allgemeinen Empfehlungen vervollständigt werden.

          Translated abstract

          Vaccinations before and during pregnancy are of great significance—through a consistent vaccination strategy, infections can be totally prevented or the course of a disease can be attenuated and risks for mother and child avoided. The recommendations for immunizations before pregnancy are adapted to the general vaccination recommendations. Two vaccinations are explicitly recommended during pregnancy. On the one hand this is immunization against seasonal influenza, which protects the pregnant woman against infection as she has a higher risk for a serious course of disease and for complications. On the other hand vaccination against pertussis is recommended, which provides protection for the newborn in the first months of life. During breastfeeding, insufficient vaccination status should be completed according to the general recommendations.

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          Most cited references6

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          Influenza in pregnancy

          Please cite this paper as: Memoli et al. (2012) Influenza in pregnancy. Influenza and Other Respiratory Viruses 00(00), 000–000. The 2009 pandemic served as a strong reminder that influenza‐induced disease can have a great impact on certain at‐risk populations and that pregnant women are one such important population. The increased risk of fatal and severe disease in these women was appreciated more than 500 years ago, and during the last century, pregnant women and their newborns have continued to be greatly affected by both seasonal and pandemic influenza. In this review, we briefly discuss the data collected both before and after the 2009 pandemic as it relates to the impact of influenza on pregnant women and their fetuses/newborns, as well as risk variables, clinical features, clues to pathophysiologic mechanisms, and approaches to treatment and prevention.
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            Pertussis vaccination in pregnancy

            C Healy (2016)
            Pertussis has had a resurgence with the highest incidence and complication rates in young infants, and deaths occurring mainly at < age 3 months. Infants are infected by older individuals whose immunity has waned. Strategies such as targeted immunization of infant caregivers have had limited success. Pertussis vaccination in pregnancy may protect infants through passive and active transfer of maternal antibodies that protect the infant until the primary immunization series. Studies show vaccinating pregnant women with acellular pertussis vaccine is safe for mother and infant, immunogenic with efficient transfer of antibodies to infants, and effective in preventing pertussis in young infants. Vaccine uptake in pregnant women is sub-optimal, but provider recommendation is the most important factor in improving vaccination rates. Studies are ongoing to determine the best timing of vaccination to protect infants, and into other strategies. Vaccinating pregnant women offers hope to prevent pertussis-related morbidity and mortality in infants worldwide.
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              Tdap vaccination during pregnancy to protect newborns from pertussis infection.

              Nowadays whooping cough (pertussis) represents one of the most prevalent vaccine-preventable diseases in Western countries; even more, it is currently on rise. In many countries, the use of acellular pertussis adult vaccine in combination with tetanus and diphtheria toxoids (Tdap) is recommended for women during pregnancy to protect newborns in the first months of life, when they are too young to be vaccinated. In Italy, vaccination of women during the third trimester of pregnancy is included in the national immunization programme (PNPV 2017-2019), though up to now, this vaccination strategy has not been efficiently implemented.
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                Author and article information

                Contributors
                sarah.hierl@klinikverbund-allgaeu.de
                Journal
                J Gynakol Endokrinol
                J Gynakol Endokrinol
                Journal Fur Gynakologische Endokrinologie (Osterreichische Ausg.)
                Springer Vienna (Vienna )
                1997-6690
                1996-1553
                1 April 2022
                : 1-5
                Affiliations
                Klinik für Gynäkologie und Geburtshilfe, Klinikverbund Allgäu gGmbH, Klinikum Kempten, Robert-Weixler-Str. 50, 87439 Kempten, Deutschland
                Article
                223
                10.1007/s41974-022-00223-0
                8972758
                71d71eb1-b420-480d-8e66-da919e5ed244
                © The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, ein Teil von Springer Nature 2022

                This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

                History
                : 3 March 2022
                Categories
                Originalien

                influenzaimpfung,pertussisimpfung,covid-19-impfung,stillzeit,impfpräventable infektionen,vaccination against influenza,vaccination against pertussis,vaccination against covid-19,breastfeeding,vaccine-preventable diseases

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