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      Research Ethics Recommendations for Whole-Genome Research: Consensus Statement

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          Abstract

          Interest in whole-genome research has grown substantially over the past few months. This article explores the challenging ethics issues associated with this work.

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          Most cited references21

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          Human genetic research: emerging trends in ethics.

          Genetic research has moved from Mendelian genetics to sequence maps to the study of natural human genetic variation at the level of the genome. This past decade of discovery has been accompanied by a shift in emphasis towards the ethical principles of reciprocity, mutuality, solidarity, citizenry and universality.
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            Ethics. Identifiability in genomic research.

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              The social and ethical issues of post-genomic human biobanks.

              Biobanking - the organized collection of biological samples and associated data - ranges in scope from small collections of samples in academic or hospital settings to large-scale national repositories. Biobanks raise many ethical concerns, to which authorities are responding by introducing specific regulations. Genomics research, which thrives on the sharing of samples and information, is affected by two prominent ethical questions: do ethical principles prevent or promote the sharing of stored biological resources? How does the advent of large-scale biobanking alter the way in which ethical issues are addressed?
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                Author and article information

                Journal
                PLoS Biol
                pbio
                plbi
                plosbiol
                PLoS Biology
                Public Library of Science (San Francisco, USA )
                1544-9173
                1545-7885
                March 2008
                25 March 2008
                : 6
                : 3
                : e73
                Author notes
                * To whom correspondence should be addressed. E-mail: tcaulfld@ 123456law.ualberta.ca
                Article
                08-PLBI-PS-0012R3
                10.1371/journal.pbio.0060073
                2270329
                18366258
                6a3846b5-484f-44ee-a942-97c706311dbd
                Copyright: © 2008 Caulfield et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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                Page count
                Pages: 6
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                Perspectives
                Custom metadata
                Caulfield T, McGuire AL, Cho M, Buchanan JA, Burgess MM, et al. (2008) Research ethics recommendations for whole-genome research: Consensus statement. PLoS Biol 6(3): e73. doi: 10.1371/journal.pbio.0060073

                Life sciences
                Life sciences

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