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      Factors influencing pain medication and opioid use in patients with musculoskeletal injuries: a retrospective insurance claims database study

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          Abstract

          Opioid use is only recommended in selected cases of musculoskeletal (MSK) injuries. We assessed factors associated with increased opioid use in MSK injuries. In a retrospective analysis of over four million workers with MSK injuries using the Swiss National Accident Insurance Fund (Suva) database, we analyzed risk factors by multivariate logistic regression. Injury severity was associated with pain medication, opioid, and strong opioid use. Whereas fractures, contusions, and ruptures had higher odds for any pain medication use, increased odds for strong opioids were observed in fractures, superficial injuries, and other injuries. Injuries of the shoulders, elbow, chest, back/spine, thorax, and pelvis/hips showed high odds for opioid use (odds ratio (OR) > 2.0). Injuries of the shoulders had higher odds for strong opioid use (OR 1.136; 95% CI 1.040–1.241). The odds for using strong opioids increased from 2008 OR 0.843 (95% confidence interval (CI) 0.798–0.891) to 2018 OR 1.503 (95% CI 1.431–1.578), compared to 2013. Injury severity, type of injury, and injured body parts influenced the use of pain medication and overall opioid use in musculoskeletal injuries. Strong opioids were more often used in fractures but also in superficial and other minor injuries, which indicates that other factors play a role when prescribing strong opioids.

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          Relationship between Nonmedical Prescription-Opioid Use and Heroin Use

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            The effectiveness and risks of long-term opioid therapy for chronic pain: a systematic review for a National Institutes of Health Pathways to Prevention Workshop.

            Increases in prescriptions of opioid medications for chronic pain have been accompanied by increases in opioid overdoses, abuse, and other harms and uncertainty about long-term effectiveness.
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              Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain

              Limited evidence is available regarding long-term outcomes of opioids compared with nonopioid medications for chronic pain.
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                Author and article information

                Contributors
                nicolas.thalmann@students.unibe.ch
                Journal
                Sci Rep
                Sci Rep
                Scientific Reports
                Nature Publishing Group UK (London )
                2045-2322
                23 January 2024
                23 January 2024
                2024
                : 14
                : 1978
                Affiliations
                [1 ]Department of Statistics, Suva (Swiss National Accident Insurance Fund), ( https://ror.org/01t56m506) Lucerne, Switzerland
                [2 ]Department of General Internal Medicine, University Hospital of Bern, Inselspital, ( https://ror.org/01q9sj412) Freiburgstrasse 18, 3010 Bern, Switzerland
                [3 ]School of Health Professions, Bern University of Applied Sciences, ( https://ror.org/02bnkt322) Murtenstrasse 10, 3008 Bern, Switzerland
                [4 ]Institute of Physiotherapy, University Hospital of Bern, Inselspital, ( https://ror.org/01q9sj412) Freiburgstrasse 18, 3010 Bern, Switzerland
                [5 ]Evidence-Based Insurance Medicine (EbIM), Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, University of Basel, ( https://ror.org/02s6k3f65) Totengässlein 3, 4051 Basel, Switzerland
                [6 ]Department of Internal Medicine, Kantonsspital Baden, ( https://ror.org/034e48p94) Baden, Switzerland
                Article
                52477
                10.1038/s41598-024-52477-7
                10805862
                38263185
                603534a1-759e-488f-a994-6335ccdcb04d
                © The Author(s) 2024

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 9 September 2023
                : 19 January 2024
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                © Springer Nature Limited 2024

                Uncategorized
                drug development,epidemiology
                Uncategorized
                drug development, epidemiology

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