Dose-response effects of oral guanidinoacetic acid on serum creatine, homocysteine and B vitamins levels.

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Abstract

Guanidinoacetic acid (GAA) is an intermediate in the biosynthesis of creatine (Cr), yet its use in human nutrition is limited due to a lack of a clear understanding of its' dose-response effect. Thus, the purpose of this study was to investigate the effect of three different dosages of GAA (1.2, 2.4 and 4.8 g/day) administered for 6 weeks on serum and urinary variables related to GAA metabolism.

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Journal

Journal ID (iso-abbrev): Eur J Nutr

Title: European journal of nutrition

Publisher: Springer Nature America, Inc

ISSN (Electronic): 1436-6215

ISSN (Print): 1436-6207

Publication date (Electronic): Dec 2014

Volume: 53

Issue: 8

Affiliations

[1 ] Exercise Physiology Laboratory, Center for Health, Exercise and Sport Sciences, Stari DIF, Deligradska 27, 11000, Belgrade, Serbia, sergej.ostojic@chess.edu.rs.

Article

DOI: 10.1007/s00394-014-0669-0

PubMed ID: 24535415

SO-VID: 5fc77e63-40a8-4a71-aea0-3d96879875bf

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