[Osteopontin (OPN), PDGF-BB (platelet-derived growth factor) and BMP-7 (bone morphogenetic protein) as markers of atherogenesis in children with chronic kidney disease (CKD) treated conservatively--preliminary results].

Abstract

Cardiovascular complications are the main cause of morbidity and mortality among patients with CKD. It is common knowledge that in atherogenesis the disorders of calcium--phosphate metabolism count. The molecules of paramount importance are OPN and BMP-7, inhibiting calcification, and PDGF-BB, facilitating this process.